三甲基-(2-壬-8-烯基-环丙氧基)-硅烷 | 101653-03-6

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 中文名称: 三甲基-(2-壬-8-烯基-环丙氧基)-硅烷
• 英文名称: trimethyl-(2-non-8-enylcyclopropyl)oxysilane
• CAS: 101653-03-6
• 化学式: C₁₅H₃₀OSi
• 分子量: 254.488
• InChiKey: YMQZHQSJUVKDIX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.14
• 重原子数：
  17.0
• 可旋转键数：
  10.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  三甲基-(2-壬-8-烯基-环丙氧基)-硅烷 在 四氯化锡 、 二甲基亚砜 作用下， 生成 2-methylene-10-undecenal
  参考文献：
  名称：

  A novel synthesis of .beta.-trichlorostannyl ketones from siloxycyclopropanes and their facile dehydrostannation affording 2-methylene ketones

  摘要：

  DOI：

  10.1021/jo00362a046

文献信息

• .beta.-Trichlorostannyl ketones and aldehydes. Preparation and facile amine-induced dehydrostannation leading to .alpha.-methylene ketones and aldehydes
  作者：Hiroyuki Nakahira、Ilhyong Ryu、Masanobu Ikebe、Yoshiaki Oku、Akiya Ogawa、Nobuaki Kambe、Noboru Sonoda、Shinji Murai

  DOI：10.1021/jo00027a008

  日期：1992.1

  Ring-opening reactions of siloxycyclopropanes 1 with SnCl4 take place under mild reaction conditions and site-selectively to give beta-trichlorostannyl ketones and aldehydes 3 in high yields. The beta-trichlorostannyl ketones and aldehydes thus obtained readily undergo base-induced dehydrotrichlorostannation at room temperature to give the corresponding alpha-methylene ketones and aldehydes 4. The reactions are quite general for amines, such as pyridine, triethylamine, N,N,N',N'-tetramethylethylenediamine (TMEDA), and 1,4-diazabicyclo[2.2.2]octane (DABCO), and the yields are good to high. One-pot conversion from siloxycyclopropanes 1 to alpha-methylene ketones or aldehydes 4 by consecutive treatment of 1 with SnCl4 and TMEDA is also successful. The H-1 NMR, C-13 NMR, Sn-119 NMR, and IR spectral properties of beta-stannyl ketones and aldehydes are also reported.
• RYU, I.;MURAI, S.;SONODA, N., J. ORG. CHEM., 1986, 51, N 12, 2389-2391
  作者：RYU, I.、MURAI, S.、SONODA, N.

  DOI：——

  日期：——