2-<(Trimethylsilyl)oxy>-1,3,7,9-decatetraene | 159111-70-3

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 2-<(Trimethylsilyl)oxy>-1,3,7,9-decatetraene
• 英文别名: [(3E,7E)-deca-1,3,7,9-tetraen-2-yl]oxy-trimethylsilane
• CAS: 159111-70-3
• 化学式: C₁₃H₂₂OSi
• 分子量: 222.403
• InChiKey: IXHFKFKZQIBZMR-NJHWEWLZSA-N

物化性质

• 沸点：
  267.6±19.0 °C(predicted)
• 密度：
  0.847±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.43
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-<(Trimethylsilyl)oxy>-1,3,7,9-decatetraene 、 Methyl 2-<2-(trimethylsilyl)ethyn-1-yl>acrylate 以 甲苯 为溶剂， 反应 16.0h， 生成 (3S*,4R*)-4-Carbomethoxy-3-(1,3-hexadien-6-yl)-4-<2-(trimethylsilyl)ethyn-1-yl>cyclohexan-1-one
  参考文献：
  名称：

  Sequential Diels-Alder Reactions on a 1,3,7,9-Tetraene: An Efficient and Stereoselective Route to the Perhydrophenanthrene Skeleton

  摘要：

  A novel, efficient, and stereoselective route to the perhydrophenanthrene skeleton is described utilizing sequential Diels-Alder reactions of methyl {(trimethylsilyl)ethynyl}aclylate with a 1,3,7,9-tetraene (bis-diene).

  DOI：

  10.1021/jo00109a014
• 作为产物：
  描述：

  (4E)-hepta-4,6-dienal 在 sodium hydride 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 为溶剂， 生成 2-<(Trimethylsilyl)oxy>-1,3,7,9-decatetraene
  参考文献：
  名称：

  An expedient and stereoselective route to the perhydrophenanthrene skeleton via sequential Diels-Alder reactions

  摘要：

  A novel and efficient stereoselective synthesis of the perhydrophenanthrene skeleton was achieved using a sequential Diels-Alder cycloaddition strategy involving enyne 10 and bis-diene 8.

  DOI：

  10.1016/s0040-4039(00)77246-7

文献信息

• An expedient and stereoselective route to the perhydrophenanthrene skeleton via sequential Diels-Alder reactions
  作者：Claude Spino、Jason Crawford

  DOI：10.1016/s0040-4039(00)77246-7

  日期：1994.8

  A novel and efficient stereoselective synthesis of the perhydrophenanthrene skeleton was achieved using a sequential Diels-Alder cycloaddition strategy involving enyne 10 and bis-diene 8.
• Sequential Diels-Alder Reactions on a 1,3,7,9-Tetraene: An Efficient and Stereoselective Route to the Perhydrophenanthrene Skeleton
  作者：Claude Spino、Jason Crawford、John Bishop

  DOI：10.1021/jo00109a014

  日期：1995.2

  A novel, efficient, and stereoselective route to the perhydrophenanthrene skeleton is described utilizing sequential Diels-Alder reactions of methyl (trimethylsilyl)ethynyl}aclylate with a 1,3,7,9-tetraene (bis-diene).