2-benzhydryl-phenetole | 110247-02-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 2-benzhydryl-phenetole
• 英文别名: 2-Benzhydryl-phenetol；2-Aethoxy-tritan；1-Benzhydryl-2-ethoxybenzene
• CAS: 110247-02-4
• 化学式: C₂₁H₂₀O
• 分子量: 288.389
• InChiKey: MHLAHVWLZFSLBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-benzhydryl-phenetole 在 氢碘酸 、 溶剂黄146 作用下， 生成 2-(diphenylmethyl)phenol
  参考文献：
  名称：

  v. Liebig; Keim, Journal fur praktische Chemie (Leipzig 1954), 1907, vol. <2> 76, p. 275,368

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 2-benzhydryl-phenetole
  参考文献：
  名称：

  v. Liebig; Keim, Journal fur praktische Chemie (Leipzig 1954), 1907, vol. <2> 76, p. 275,368

  摘要：

  DOI：

文献信息

• Evaluation of potential organ culture media for eye banking using a human corneal endothelial cell growth assay
  作者：Torben Møller-Pedersen、Ulrike Hartmann、Niels Ehlers、Katrin Engelmann

  DOI：10.1007/s004170100354

  日期：2001.10

  Background: To evaluate the ability of different commercially available cell Culture media to induce proliferation and morphological changes in primary cultures of human corneal endothelial cells (HCEC). This screening model was used in an attempt to establish a rational basis for the development of well-defined, serum-free preservation media for long-term organ culture of human donor corneas. Methods: A total of I I different culture media enriched with 0%, 2%, 5%, and 10% fetal calf serum (FCS) were compared. The test media were divided into three groups: Group 1: Media based on minimal essential medium (MEM), currently used for long-term corneal organ culture in European eye banks; Group 2: F99-based media, enriched for growth of corneal endothelial cells at serum-reduced conditions; and Group 3: Media designed for growth of special cell types or for short-term corneal organ culture. The growth-promoting capacity of each test medium was quantified using an HCEC proliferation assay, whereas changes in cell morphology were evaluated by phase-contrast microscopy. Results: The morphological characteristics of HCEC were best maintained in the group of F99-based media, which also induced the highest level of cell proliferation under serum-reduced conditions. Specifically, the medium F99-Sr (F99 enriched with ascorbic acid, insulin, bFGF, transferrin. selenium, and lipids) induced a two- to three-fold higher HCEC density at both 0% and 2% FCS when compared to all other test media, and it also maintained the most endothelial cell-like morphology. Also, at higher serum concentrations (5% and 10% FCS), the cell growth was most prominent in F99-Sr, as well as in the medium SFM that originally was designed for serum-free growth of vascular endothelial cells. Conclusion: This study suggests that the media F99-Sr and SFM should be further tested and refined as potential new storage solutions for long-term corneal organ culture at physiological temperatures.
• 852. Free radicals and radical stability. Part XIV. (Ethoxyphenyl)diphenylmethanols and the free radical (o-ethoxyphenyl)-diphenylmethyl
  作者：S. T. Bowden、D. T. Zalichi

  DOI：10.1039/jr9570004240

  日期：——
• Schmidt,O., Diss. Heidelberg <1898>, S. 29
  作者：Schmidt,O.

  DOI：——

  日期：——
• v. Liebig; Keim, Journal fur praktische Chemie (Leipzig 1954), 1907, vol. <2> 76, p. 275,368
  作者：v. Liebig、Keim

  DOI：——

  日期：——