1-ethylsulfinyl-1-methylsulfanylprop-1-ene

• 分子结构分类: 有机化合物 - 有机硫化合物 - 亚砜
• 英文名称: 1-ethylsulfinyl-1-methylsulfanylprop-1-ene
• 英文别名: (E)-1-ethylsulfinyl-1-methylsulfanylprop-1-ene
• 化学式: C₆H₁₂OS₂
• 分子量: 164.293
• InChiKey: XLQCMDRZHFXTLU-GQCTYLIASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  61.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  methyl dithiopropionate 、 碘乙烷 在 甲基锂 、 trans-3-(1,1-dimethylethyl)-3-methyl-2-(phenylsulfonyl)oxaziridine 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 反应 0.58h， 生成 1-ethylsulfinyl-1-methylsulfanylprop-1-ene 、 1-ethylsulfinyl-1-methylsulfanylprop-1-ene
  参考文献：
  名称：

  Highly Chemoselective Oxidation of Dithioester Enethiolates to Sulfenates:  Application to the Synthesis of Ketene Dithioacetal S-Oxides

  摘要：

  Enethiolates derived from dithioesters were efficiently converted into the corresponding vinyl sulfenates by oxidation with a unique N-sulfonyloxaziridine la derived from pinacolone. Subsequent alkylation with alkyl halides led to ketene dithioacetal S-oxides in good to excellent yields.

  DOI：

  10.1021/jo0492362

文献信息

• Highly Chemoselective Oxidation of Dithioester Enethiolates to Sulfenates:  Application to the Synthesis of Ketene Dithioacetal <i>S</i>-Oxides
  作者：Franck Sandrinelli、Gaëlle Fontaine、Stéphane Perrio、Pierre Beslin

  DOI：10.1021/jo0492362

  日期：2004.10.1

  Enethiolates derived from dithioesters were efficiently converted into the corresponding vinyl sulfenates by oxidation with a unique N-sulfonyloxaziridine la derived from pinacolone. Subsequent alkylation with alkyl halides led to ketene dithioacetal S-oxides in good to excellent yields.