Melamine trisulfonic acid, which is easily prepared by the reaction of melamine with neat chlorosulfonic acid, is able to efficiently catalyze the chemoselective methoxymethylation of alcohols with dimethoxymethane (DMM). All reactions were performed under mild and completely heterogeneous reaction conditions in good to high yields.
三聚氰胺三
磺酸很容易通过
三聚氰胺与纯
氯磺酸反应制备,能够有效地催化醇与二甲氧基
甲烷(
DMM)的
化学选择性甲氧基甲基化。所有反应均在温和且完全非均相的反应条件下以良好至高产率进行。