6-[4-(phenylazo)phenoxy]hexyl methacrylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: 6-[4-(phenylazo)phenoxy]hexyl methacrylate
• 英文别名: 6-(4-(phenyldiazenyl)phenoxy)hexan-1-ol；methacrylohydroxyhexane azobenzene；6-(4-(phenyldiazenyl)phenoxy)hexyl methacrylate；6-(4-phenyldiazenylphenoxy)hexyl 2-methylprop-2-enoate
• 化学式: C₂₂H₂₆N₂O₃
• 分子量: 366.46
• InChiKey: HREFEKMBLJVPDQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  27
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  60.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  4-N-苯基苯酰胺 在 potassium carbonate 、 三乙胺 、 potassium iodide 作用下， 以 二氯甲烷 为溶剂， 反应 26.5h， 生成 6-[4-(phenylazo)phenoxy]hexyl methacrylate
  参考文献：
  名称：

  Smart azobenzene-containing tubular polymersomes: fabrication and multiple morphological tuning

  摘要：

  通过自组装，制备了几种含有偶氮苯的新型管状聚合物体，其形状可以通过改变化学结构、自组装条件和外部刺激来精确调节。

  DOI：

  10.1039/d0cc01934h

文献信息

• Light-triggered reversible assemblies of azobenzene-containing amphiphilic copolymer with β-cyclodextrin-modified hollow mesoporous silica nanoparticles for controlled drug release
  作者：Xiao Mei、Shun Yang、Dongyun Chen、Najun Li、Hua Li、Qingfeng Xu、Jianfeng Ge、Jianmei Lu

  DOI：10.1039/c2cc33995a

  日期：——

  Hollow mesoporous silica nanoparticles (HMSs) were modified by β-cyclodextrin via a “click” reaction, an amphiphilic copolymer with a trans-azobenzene structure was then assembled onto β-cyclodextrin to cover the surface of the HMSs. The prepared nanocomposites can release drugs in a “release-stop-release” manner by converting light irradiation.

  通过“点击”反应，将β-环糊精修饰到空心中孔二氧化硅纳米颗粒（HMSs）上，随后在β-环糊精上组装具有反式偶氮苯结构的 amphiphilic copolymer（双亲共聚物），以覆盖HMSs的表面。制备得到的纳米复合材料可以通过光照射转换以实现“释放-停止-释放”的药物释放模式。
• Synthesis of ferrocene and azobenzene-based copolymers P(FHEMA-co-MAZOHE)s and their redox and photo-responsive properties
  作者：Amin Khan、Haojie Yu、Li Wang、Pavel A. Zhizhko、Dmitry N. Zarubin、Dmitry A. Lemenovskiy、Fazal Haq、Muhammad Usman、Ahsan Nazir、Kaleem-ur-Rehman Naveed

  DOI：10.1016/j.jorganchem.2019.05.009

  日期：2019.9

  Herein, poly(2-(methacryloyloxy) ethyl ferrocene carboxylate-co-(methacrylohydroxyhexane azobenzene) s) (P(FHEMA-co-MAZOHE)s) were prepared by random copolymerization and were characterized by proton nuclear magnetic resonance (H-1 NMR) and gel permeation chromatography (GPC) to confirm the structures and molecular weights respectively. Thermal variations were analyzed by thermogravimetric (TG), differential thermogravimetric (DTG) and differential scanning calorimetry (DSC) techniques. Finally, redox and photo stimuli-responsive properties were confirmed by cyclic voltammetry (CV) and ultraviolet-visible spectroscopy (UV-vis) respectively. The results revealed that (P(FHEMA-co-MAZOHE) s) can be useful as information storage materials. (c) 2019 Elsevier B.V. All rights reserved.