5-(allyloxy)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 5-(allyloxy)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline
• 英文别名: 10-methoxy-2,2,4-trimethyl-5-prop-2-enoxy-1,5-dihydrochromeno[3,4-f]quinoline
• 化学式: C₂₃H₂₅NO₃
• 分子量: 363.456
• InChiKey: SLNIDRAJTYTJAT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  39.7
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysen-5-ol 、 烯丙基三甲基硅烷 以a Lewis acid to provide 5-(allyloxy)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline的产率得到5-(allyloxy)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline
  参考文献：
  名称：

  Process for the preparation of 5-(substituted)-10 methoxy-2,2,4-trimethyl-2,5-dihydro- 1H-chromeno [3,4-f] quinolines and derivatives thereof

  摘要：

  本发明涉及一种高效的方法，用于制备5-（取代基）-10-甲氧基-2,2,4-三甲基-2,5-二氢-1H-色烯[3,4-f]喹啉。

  公开号：

  US20030069427A1

文献信息

• Process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-F]quinolines and derivatives thereof
  申请人：Abbott Laboratories

  公开号：US06518430B1

  公开（公告）日：2003-02-11

  The present invention relates to an efficient process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinolines.

  本发明涉及一种高效的制备5-(取代基)-10-甲氧基-2,2,4-三甲基-2,5-二氢-1H-咖啡因[3,4-f]喹啉的方法。
• Process for the preparation of 5-(substituted)-10 methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno [3,4-F] quinolines and derivatives thereof
  申请人：——

  公开号：US06673930B2

  公开（公告）日：2004-01-06

  The present invention relates to an efficient process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinolines.

  本发明涉及一种高效的方法，用于制备5-(取代)-10-甲氧基-2,2,4-三甲基-2,5-二氢-1H-咔啉[3,4-f]喹啉。
• US6518430B1
  申请人：——

  公开号：US6518430B1

  公开（公告）日：2003-02-11
• US6673930B2
  申请人：——

  公开号：US6673930B2

  公开（公告）日：2004-01-06
• [EN] A PROCESS FOR THE PREPARATION OF 5-(SUBSTITUTED)-10-METHOXY-2,2,4-TRIMETHYL-2,5-DIHYDRO-1H-CHROMENO[3,4-F]QUINOLINES AND DERIVATIVES THEREOF<br/>[FR] PROCEDE DE PREPARATION DE 5-(SUBSTITUEES)-10-METHOXY-2,2,4-TRIMETHYL-2,5-DIHYDRO-1H-CHROMENO[3,4-F]QUINOLEINES ET LEURS DERIVES
  申请人：ABBOTT LAB

  公开号：WO2003027117A1

  公开（公告）日：2003-04-03

  The present invention relates to an efficient process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinolines.