Aluminum(III) chloride hexahydrate

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 后过渡金属盐
• 英文名称: Aluminum(III) chloride hexahydrate
• 英文别名: aluminum trichloride hexahydrate；aluminium chloride hexahydrate；aluminum chloride hexahydrate；Aluminum;chloride;hydrate
• 化学式: Al*3Cl*6H₂O
• 分子量: 241.432
• InChiKey: OEDSJEJJJKFPLD-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  3
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Aluminum(III) chloride hexahydrate 、 4-氨基苯乙酸 以 5,5-dimethyl-1,3-cyclohexadiene 为溶剂， 生成 对乙酰氨基酚
  参考文献：
  名称：

  Production of p-acetylaminophenol from p-aminophenyl acetate

  摘要：

  在存在醋酸或磷酸等酸的情况下，p-氨基苯乙酸酯发生异构化反应，生成p-乙酰氨基苯酚。

  公开号：

  US05221769A1
• 作为试剂：
  描述：

  苯乙酮 在 Aluminum(III) chloride hexahydrate 、 urea-hydrogen peroxide 、 1-butyl-3-methylimidazolium Tetrafluoroborate 作用下， 反应 6.0h， 以77%的产率得到alpha-氯乙酰苯
  参考文献：
  名称：

  在离子液体中使用氯化铝/尿素-过氧化氢对芳基酮进行有效的 α-氯化

  摘要：

  摘要 在 [bmim]BF4 离子液体中，使用六水氯化铝和过氧化氢可实现芳基酮有效的 α-氯化反应生成相应的 α-氯酮。

  DOI：

  10.1080/00397910500449641

文献信息

• Benzalicyclic carboxylic acid derivative
  申请人：Takeda Chemical Industries, Ltd.

  公开号：US03953500A1

  公开（公告）日：1976-04-27

  Compounds of the formula: ##SPC1## Wherein R.sup.1 is an aryl group which may be substituted, R.sup.2 is hydrogen or a lower alkyl group having 1 to 4 carbon atoms and n is 1 or 2, or derivatives at the carboxyl function thereof, are useful as medicines such as antipyretics, analgesics and anti-inflammatory agents.

  公式为：##SPC1## 其中 R.sup.1 是可能被取代的芳基团，R.sup.2 是氢或具有1至4个碳原子的较低烷基团，n 为1或2，或其羧基功能的衍生物，可用作药物，如退烧药、止痛药和抗炎药。
• Anti-inflammatory 1-oxo-isoindoline derivatives and processes for their
  申请人：Fuji Chemical Industry Company Limited

  公开号：US04116972A1

  公开（公告）日：1978-09-26

  Hydrogenated 1-oxo-isoindoline derivatives having a strong anti-inflammatory activity may be prepared by reducing the corresponding hydrogenated 1,3-dioxo-isoindoline derivative to the 3-hydroxy-1-oxo-isoindoline derivative and then further reducing, dehydrating or hydrolizing this compound.

  具有强抗炎活性的氢化1-氧代异吲哚衍生物可以通过将相应的氢化1,3-二氧代异吲哚衍生物还原为3-羟基-1-氧代异吲哚衍生物，然后进一步还原、脱水或水解该化合物来制备。
• Superior catalysts for preparation of
  申请人：Pfizer Inc.

  公开号：US04851548A1

  公开（公告）日：1989-07-25

  Boric acid or aluminum salts, especially aluminum chloride, aluminum sulfate and aluminum nitrate and hydrates of said salts, are superior catalysts for preparation of 3-amino-2,2,4,4-tetramethylthietane via the Leuckart reaction.

  硼酸或铝盐，特别是氯化铝、硫酸铝、硝酸铝及其水合物，是通过Leuckart反应制备3-氨基-2,2,4,4-四甲基噻吩烷的优良催化剂。
• Transdermal treatment for pain and inflammation with
  申请人：A. H. Robins Company, Incorporated

  公开号：US04683242A1

  公开（公告）日：1987-07-28

  A method is disclosed for treating pain and/or inflammation by transdermal administration of 2-amino-3-benzoylbenzeneacetic acids, salts and esters having the formula ##STR1## wherein R.sup.1 is hydrogen, loweralkyl or a pharmaceutically acceptable cation; R.sup.2 is hydrogen, halogen, loweralkyl or loweralkoxy; R.sup.3, R.sup.4 and R.sup.5 are hydrogen or loweralkyl; X is hydrogen, halogen, loweralkyl, hydroxy, loweralkoxy, nitro, trifluoromethyl or loweralkylthio; Y is hydrogen, loweralkyl, loweralkoxy, nitro or trifluoromethyl and hydrates and alcoholates thereof.

  本发明公开了一种通过经皮给予2-氨基-3-苯甲酰基苯乙酸、盐和酯来治疗疼痛和/或炎症的方法，其化学式为##STR1##其中R.sup.1为氢，低烷基或药学上可接受的阳离子；R.sup.2为氢，卤素，低烷基或低烷氧基；R.sup.3，R.sup.4和R.sup.5为氢或低烷基；X为氢，卤素，低烷基，羟基，低烷氧基，硝基，三氟甲基或低烷硫基；Y为氢，低烷基，低烷氧基，硝基或三氟甲基和其水合物和醇盐。
• Glucose and glucuronic acid interactions with hydrolysed aluminium(III)
  作者：M. Tonković、H. Bilinski

  DOI：10.1016/0277-5387(94)00341-b

  日期：1995.4

  Interaction of D-glucose and b-glucuronic acid and of hydrolysed aluminium (III) has been studied in 0.6 M NaCl solution, Isolated solids were analysed and studied by means of IR and C-13 NMR spectroscopy. Soluble samples close to the precipitation boundary were examined with UV spectroscopy. Glucuronic acid showed higher affinity toward binding to the aluminium hydroxide matrix than glucose, It is concluded that glucose is bound via hydroxyl groups on C(4) and C(6) atoms in alpha- and beta-pyranose forms. Glucuronic acid is bound in alpha- and beta-pyranose forms via the carboxyl group and the hydroxyl group on the C(4) atom.