二(苯基)-(4-苯基苯基)甲醇 | 38696-14-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 中文名称: 二(苯基)-(4-苯基苯基)甲醇
• 英文名称: 4-biphenylyldiphenylmethanol
• 英文别名: Biphenylyl-(4)-diphenyl-methanol；4-Phenyl-triphenylmethanol；p-Biphenylyl-diphenyl-methanol；Methanol, 4-biphenyldiphenyl-；diphenyl-(4-phenylphenyl)methanol
• CAS: 38696-14-9
• 化学式: C₂₅H₂₀O
• 分子量: 336.433
• InChiKey: YIQKLMVZSXYWOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2906299090

反应信息

• 作为反应物：
  描述：

  二(苯基)-(4-苯基苯基)甲醇 在 乙酰氯 作用下， 以 甲苯 为溶剂， 生成 Biphenyl-4-yl(diphenyl)methyl chloride
  参考文献：
  名称：

  Sterically hindered free radicals. 14. Substituent-dependent stabilization of para-substituted triphenylmethyl radicals

  摘要：

  DOI：

  10.1021/ja00273a034
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium carbonate 作用下， 生成 二(苯基)-(4-苯基苯基)甲醇
  参考文献：
  名称：

  Skraup; Freundlich, Chemische Berichte, 1922, vol. 55, p. 1080

  摘要：

  DOI：

文献信息

• Superacid-Catalyzed Reaction of Substituted Benzaldehydes with Benzene
  作者：Shinichi Saito、Tomohiko Ohwada、Koichi Shudo

  DOI：10.1021/jo960665c

  日期：1996.11.15

  Benzaldehydes bearing an electron-withdrawing group reacted with 2 equiv of benzene in the presence of a superacid, trifluoromethanesulfonic acid, to give substituted triphenylmethane in good yields. On the other hand, benzaldehydes bearing an electron-donating or a neutral group reacted under the similar conditions to give unsubstituted diphenylmethane and triphenylmethanol, together with substituted

  在超酸三氟甲磺酸的存在下，带有吸电子基团的苯甲醛与2当量的苯反应，以高收率得到取代的三苯甲烷。另一方面，带有给电子或中性基团的苯甲醛在相似的条件下反应生成未取代的二苯基甲烷和三苯基甲醇，以及取代的苯。我们提出了这一反应的新机制，其中涉及烷基转移作为关键步骤。
• Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides
  作者：Soneela Asghar、Sanita B. Tailor、David Elorriaga、Robin B. Bedford

  DOI：10.1002/anie.201710053

  日期：2017.12.18

  Readily accessed cobalt pre-catalysts with N-heterocyclic carbene ligands catalyze the Suzuki cross-coupling of aryl chlorides and bromides with alkyllithium-activated arylboronic pinacolate esters. Preliminary mechanistic studies indicate that the cobalt species is reduced to Co0 during the reaction.

  具有N-杂环卡宾配体的易于使用的钴预催化剂催化芳基氯化物和溴化物与烷基锂活化的芳基硼酸频哪醇酸酯的Suzuki交叉偶联。初步的机理研究表明，在反应过程中钴物种被还原为Co0。
• Aspects of crystal engineering arising from packing behavior of functional mono para-substituted trityl compounds
  作者：Ingo Knepper、Wilhelm Seichter、Konstantinos Skobridis、Vassiliki Theodorou、Edwin Weber

  DOI：10.1039/c5ce00871a

  日期：——

  Four trityl compounds differing both in the functional group (OH, OMe, NH2) at the specific trityl carbon and a para substituent, being bromine or phenyl at one of the phenyl groups, have been prepared and structurally studied by means of single crystal X-ray diffraction and making use of Hirshfeld surface analysis. Compared to the structures of corresponding prototypes and analogues, specific interaction modes and packing motifs including cluster aggregates as well as non-cluster type structures depending on the substitution and involving polymorphism were found, opening potential trend prediction with reference to crystal engineering being useful in this compound class.

  四种trityl化合物已通过单晶X射线衍射和Hirshfeld表面分析进行了制备和结构研究，这些化合物在特定的trityl碳上具有不同官能团（OH、OMe、NH2），并且在其中一个苯环上具有溴或苯基的para取代基。与相应的原型和类似物的结构相比，发现了特定的相互作用模式和包装模式，包括簇聚集和非簇类型结构，这些结构取决于取代基并涉及多晶型现象，打开了与晶体工程相关的潜在趋势预测，这对这类化合物具有实用性。
• <i>p</i>‐Methoxy Diphenylmethanol (MDPM), <i>p</i>‐Phenyl Diphenylmethanol (PDPM), and <i>p</i>‐Phenylphenyl Diphenylmethanol (PPDPM)—Protecting Groups for Alcohols—Protection and Deprotection
  作者：G. V. M. Sharma、T. Rajendra Prasad、Rakesh、B. Srinivas

  DOI：10.1081/scc-120028367

  日期：2004.12.31

  Abstract Two new protecting groups viz. p‐phenyl diphenylmethanol (PDPM) and p‐phenylphenyl diphenylmethanol (PPDPM) were prepared and utilized along with p‐methoxy diphenylmethanol (MDPM), for the protection of alcohols in the presence of Yb(OTf)3. Deprotection of the above ethers was achieved using DDQ or CF3COOH. #IICT Communication Number: 021001.

  摘要 两个新的保护基团，即。制备对苯基二苯基甲醇 (PDPM) 和对苯基苯基二苯基甲醇 (PPDPM) 并将其与对甲氧基二苯基甲醇 (MDPM) 一起用于在 Yb(OTf)3 存在下保护醇。使用DDQ或CF 3 COOH实现上述醚的脱保护。#IICT 通讯号码：021001。
• Carbocation catalysed ring closing aldehyde–olefin metathesis
  作者：Shengjun Ni、Johan Franzén

  DOI：10.1039/c8cc06734a

  日期：——

  4-Phenylphenyl-diphenylmethylium tetrafluoroborate catalyses a rare high yielding intramolecular aldehyde–olefin metathesis of enals under mild reaction conditions and low catalyst loading.

  在温和的反应条件和较低的催化剂负载下，4-苯基二苯基甲基四氟硼酸盐催化了一种罕见的高产率烯醛分子内醛-烯烃复分解反应。