1-(2-羟基-2-甲基丙氧基)-2,2,6,6-四甲基哌啶-4-醇 | 290821-83-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 1-(2-羟基-2-甲基丙氧基)-2,2,6,6-四甲基哌啶-4-醇
• 英文名称: 1-(2-hydroxy-2-methylpropoxy)-4-hydroxy-2,2,6,6-tetramethylpiperidine
• 英文别名: 1-(2-hydroxy-2-methyl-propoxy)-2,2,6,6-tetramethylpiperidin-4-ol；4-hydroxy-1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidine；1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethyl-4-hydroxypiperidine；4-Piperidinol, 1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethyl-；1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidin-4-ol
• CAS: 290821-83-9
• 化学式: C₁₃H₂₇NO₃
• 分子量: 245.362
• InChiKey: FYQOHJWNKFULEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-(2-羟基-2-甲基丙氧基)-2,2,6,6-四甲基哌啶-4-醇 在 calcium hypochlorite 、 IRA 900 resin 作用下， 以 四氯化碳 为溶剂， 反应 7.0h， 以88%的产率得到1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethyl-piperidin-4-one
  参考文献：
  名称：

  [EN] WATER COMPATIBLE STERICALLY HINDERED ALKOXYAMINES AND HYDROXY SUBSTITUTED ALKOXYAMINES
  [FR] ALCOXYAMINES STERIQUEMENT ENCOMBREES ET ALCOXYAMINES HYDROXY SUBSTITUEES HYDROCOMPATIBLES

  摘要：

  通过具有亲水性的特定骨架，使具有立体位阻的烷氧胺和羟基取代的烷氧胺稳定剂化合物与水相容。其中，立体位阻胺的示例为以下公式，其中 E 和 E’ 为 2-羟基环己氧基、2-羟基-2-甲基丙氧基、苄氧基、甲氧基、丙氧基、己氧基、庚氧基、辛氧基或环己氧基，Rx 为例如 -NH2+CH2CH20H Cl-, -NH3+ -OAc, =NOH, -NHCH(CH3)COO-K+,- NHCH2CH2NH(CH3)2+ -OAC, -NHCH2CH2SO3-K+, -NHCH(COO- K+)CH2CH2SCH3, -NHCH2COO- K+, -OCH(CH3)COO-K+, -OCH2CH2NH(CH3)2+ -OAC, -OCH2CH2SO3-K+, -OCH(COO- K+)CH2CH2SCH3 或 -OCH2COO-K+，R5 包括重复单元 -(OCH2CH2)-, -(OCH2CH2(CH3))-,-(CH2CHCOOH)-, -(CH2C(CH3)COOH)-, -(CH2CHCOOCH3)-, -(NHCH2CH2)-, -(CH2CHOH)-, -(CH2CHCONH2)- 或 -(CH2CH(NHCOH))-. 这些化合物在稳定水性聚合物体系抵抗氧化、热和光辐射的有害影响方面特别有效。这些化合物例如在稳定水性涂料、水性油墨、水性喷墨介质和光固化水性系统方面非常有效。

  公开号：

  WO2004076419A1
• 作为产物：
  描述：

  阻聚剂701 、 二丙酮醇 以10%的产率得到1-(2-羟基-2-甲基丙氧基)-2,2,6,6-四甲基哌啶-4-醇
  参考文献：
  名称：

  WO2008/3602

  摘要：

  公开号：

文献信息

• Hindered Amine salt compounds
  申请人：Wood Marvin G.

  公开号：US20080221332A1

  公开（公告）日：2008-09-11

  The present invention relates water-soluble hindered amine compounds of the general formula (I): wherein G 1 and G 2 are independently alkyl of 1 to 4 carbon atoms or are together pentamethylene; Z 1 and Z 2 are each methyl, or Z 1 and Z 2 together form an unsubstituted linking moiety or a linking moiety substituted by one or more groups selected from an ester, ether, hydroxy, oxo, cyanohydrin, amide, amino, carboxy or an urethane group; E is alkoxy of 1 to 18 carbon atoms, cycloalkoxy of 5 to 12 carbon atoms or aralkoxy of 7 to 15 carbon atoms, or E is —O-T-(OH) b ; T is a straight or branched chain alkylene of 1 to 18 carbon atoms, cycloalkylene of 5 to 18 carbon atoms, cycloalkenylene of 5 to 18 carbon atoms, a straight or branched chain alkylene of 1 to 4 carbon atoms substituted by phenyl or by phenyl substituted by one or two alkyl groups of 1 to 4 carbon atoms; b is 1, 2 or 3 with the proviso that b cannot exceed the number of carbon atoms in T, and when b is 2 or 3, each hydroxyl group is attached to a different carbon atoms of T; and, HY is an inorganic or organic acid; and, wherein the total charge of cations is equal to the total charge of anions.

  本发明涉及一般式(I)的水溶性受阻胺化合物：其中G1和G2分别是1至4个碳原子的烷基，或者一起是戊亚甲基；Z1和Z2分别是甲基，或者Z1和Z2一起形成一个未取代的连接基或一个由酯、醚、羟基、酮基、氰水合物、酰胺、氨基、羧基或脲基中选择的一个或多个基团取代的连接基；E是1至18个碳原子的烷氧基，5至12个碳原子的环烷氧基或7至15个碳原子的芳基氧基，或者E是—O-T-(OH)b；T是1至18个碳原子的直链或支链烷基，5至18个碳原子的环烷基，5至18个碳原子的环烯基，1至4个碳原子的直链或支链烷基，其被苯基取代，或者被一个或两个1至4个碳原子的烷基取代的苯基取代；b是1、2或3，但b不能超过T中的碳原子数，当b为2或3时，每个羟基连接到T的不同碳原子；HY是无机或有机酸；总阳离子电荷等于总阴离子电荷。
• Stabilized body care products, household products, textiles and fabrics
  申请人：Lupia A. Joseph

  公开号：US20060264345A1

  公开（公告）日：2006-11-23

  Disclosed are stabilized body care products, household products, textiles and fabrics which comprise certain sterically hindered amine salt compounds. Dyed products and articles are effectively stabilized against color degradation. The products are for example skin-care products, hair-care products, dentifrices, cosmetics, laundry detergents and fabric softeners, non-detergent based fabric care products, household cleaners and textile-care products.

  披露了包含特定立体位阻胺盐化合物的稳定的身体护理产品、家用产品、纺织品和织物。染色产品和物品能够有效地抵抗颜色退色。这些产品例如包括皮肤护理产品、头发护理产品、牙膏、化妆品、洗衣液和柔顺剂、非洗涤剂基础的织物护理产品、家用清洁剂和纺织品护理产品。
• USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS AND/OR AS STABILIZERS FOR PLASTICS, FLAME-RETARDANT AND/OR STABILIZED PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS
  申请人：FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

  公开号：US20170260366A1

  公开（公告）日：2017-09-14

  The present invention relates to the use of phosphorous-containing organic oxyimides according to the general formula (I) as flame retardant for plastic materials, as radical generators in plastic materials and/or stabilisers for plastics. In addition, the present invention relates to a flame-retardant plastic material moulding compound in which the previously described phosphorous-containing organic oxyimides are integrated, and also to a method for the production of the previously mentioned plastic material composition. Furthermore, the present invention relates to a moulded article, a paint or a coating from the previously mentioned flame-retardant plastic material composition.

  本发明涉及根据一般式(I)的含磷有机氧亚胺化合物作为塑料材料的阻燃剂，作为塑料材料中的自由基发生剂和/或塑料的稳定剂。此外，本发明涉及一种阻燃塑料材料成型复合物，其中集成了前述的含磷有机氧亚胺化合物，并且涉及一种用于制备前述塑料材料组合物的方法。此外，本发明涉及一种从前述阻燃塑料材料组合物制成的成型制品、涂料或涂层。
• Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith
  申请人：Ciba Specialty Chemicals Corporation

  公开号：US06392041B1

  公开（公告）日：2002-05-21

  Hindered amines substituted on the N-atom with an —O—E—OH moiety are particularly effective in stabilizing polyolefin and automotive coating compositions against the deleterious effects of oxidative, thermal and actinic radiation where the presence of the OH group on the compounds adds important properties not attainable by the use of normal —O—E moieties.

  N-原子上带有—O—E—OH官能团的受阻胺，在稳定聚烯烃和汽车涂料组分抵抗氧化、热和光化辐射的有害影响方面特别有效，其中化合物上OH基团的存在赋予了无法通过使用普通—O—E官能团获得的重要的特性。
• Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith
  申请人：——

  公开号：US20030004235A1

  公开（公告）日：2003-01-02

  2H-Benzotriazole UV absorbers substituted at the 3-position and/or the 5-position of the phenyl ring by a phenyl moiety which is substituted by a heteroatom are particularly photostable in automotive coatings, and are of low color and exhibit low volatility in thermoplastic compositions.

  3-位和/或5-位被苯基环上的苯基取代的2H-苯并三唑紫外线吸收剂，其被异原子取代的苯基特别在汽车涂料中具有光稳定性，并且在热塑性复合材料中具有低色度和低挥发性。