6-Methoxy-2-oxaspiro[3.3]heptane

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环丁烷
• 英文名称: 6-Methoxy-2-oxaspiro[3.3]heptane
• 英文别名: 6-methoxy-2-oxaspiro[3.3]heptane
• 化学式: C₇H₁₂O₂
• 分子量: 128.17
• InChiKey: BUNGWXWBSRHTKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• TANK-BINDING KINASE INHIBITOR COMPOUNDS
  申请人：Du Zhimin

  公开号：US20150344473A1

  公开（公告）日：2015-12-03

  Compounds having the following formula (I) and methods of their use and preparation are disclosed:

  公开具有以下式（I）的化合物及其使用和制备方法：
• C-GLYCOSIDE DERIVATIVES
  申请人：Xuanzhu Pharma Co., Ltd.

  公开号：EP2725031A1

  公开（公告）日：2014-04-30

  The present invention involves a compound represented by general formula (I), a derivative thereof and a use thereof: wherein R1, R2, R3, R4, R5a, R5b, R5c and X are defined as in the description.

  本发明涉及通式 (I) 所代表的化合物、其衍生物及其用途： 其中 R1、R2、R3、R4、R5a、R5b、R5c 和 X 的定义如说明书所述。
• [EN] OXA-THIA-BICYCLO[3.2.1]OCTANE DERIVATIVE, PREPARATION METHOD, AND USE OF SAME<br/>[FR] DÉRIVÉ D'OXA-THIA-BICYCLO[3.2.1]OCTANE, PROCÉDÉ DE PRÉPARATION ET UTILISATION DE CELUI-CI
  申请人：SICHUAN HAISCO PHARMACEUTICAL CO LTD

  公开号：WO2014206349A1

  公开（公告）日：2014-12-31

  本发明涉及氧杂-硫杂-双环[3.2.1]辛烷衍生物、制备方法及其用途，具体而言涉及通式（I）所示的氧杂-硫杂-双环[3.2.1]辛烷衍生物或水合物、溶剂化物、其立体异构体、药学上可接受的盐、共晶体、前药、制备方法、含有该衍生物的药物组合物以及作为制备钠依赖性葡糖转运蛋白（SGLT）抑制剂的医药用途，其中通式（I）中各取代基的定义与说明书的定义相同。
• AMINO PRYAN RING DERIVATIVE AND COMPOSITION AND USE THEREOF
  申请人：Sichuan Haisco Pharmaceutical Co., Ltd.

  公开号：US20170121338A1

  公开（公告）日：2017-05-04

  The present disclosure relates to an amino pyran ring derivative and a composition and use thereof, and in particular, to an amino pyran ring derivative represented by general formula (I) or a stereoisomer, a pharmaceutically acceptable salt or a prodrug thereof, a pharmaceutical composition comprising the derivative, and their medical use in the manufacture of a di-peptidyl peptidase IV (DPP-IV) inhibitor, in formula (I) the substituents are defined the same as those in the specification.
• N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：US20200289507A1

  公开（公告）日：2020-09-17

  The present invention relates to derivatives of formula (I) wherein (R 1 ) n , R 2 , R 3 , R 4a , R 4b , R 5a , R 5b and Ar 1 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.