2-(3-Hydroxy-6-oxoxanthen-9-yl)-5-[[2-oxo-2-[[5-(6-pyridin-2-yl-1,2,4,5-tetrazin-3-yl)pyridin-2-yl]amino]ethyl]carbamothioylamino]benzoic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2-(3-Hydroxy-6-oxoxanthen-9-yl)-5-[[2-oxo-2-[[5-(6-pyridin-2-yl-1,2,4,5-tetrazin-3-yl)pyridin-2-yl]amino]ethyl]carbamothioylamino]benzoic acid
• 英文别名: 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[[2-oxo-2-[[5-(6-pyridin-2-yl-1,2,4,5-tetrazin-3-yl)pyridin-2-yl]amino]ethyl]carbamothioylamino]benzoic acid
• 化学式: C₃₅H₂₃N₉O₆S
• 分子量: 697.7
• InChiKey: AWBWGKBBVKEETD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  51
• 可旋转键数：
  8
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.03
• 拓扑面积：
  246
• 氢给体数：
  5
• 氢受体数：
  13

文献信息

• D-Amino Acid Derivative-Modified Peptidoglycan and Methods of Use Thereof
  申请人：The Regents of the University of California

  公开号：US20140170183A1

  公开（公告）日：2014-06-19

  The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria or peptidoglycan; and methods of using the modified bacteria or peptidoglycan. The modified D-amino acids include a bioorthogonal functional group such as an azide, an alkyne or a norbornene group. Also provided are modified peptidoglycans conjugated to a molecule of interest via a linker.
• D-AMINO ACID DERIVATIVE-MODIFIED PEPTIDOGLYCAN AND METHODS OF USE THEREOF
  申请人：The Regents of the University of California

  公开号：US20170021013A1

  公开（公告）日：2017-01-26

  The present disclosure provides modified bacteria and modified peptidoglycan comprising modified D-amino acids; compositions comprising the modified bacteria or peptidoglycan; and methods of using the modified bacteria or peptidoglycan. The modified D-amino acids include a bioorthogonal functional group such as an azide, an alkyne or a norbornene group. Also provided are modified peptidoglycans conjugated to a molecule of interest via a linker.
• US9303068B2
  申请人：——

  公开号：US9303068B2

  公开（公告）日：2016-04-05
• US9789180B2
  申请人：——

  公开号：US9789180B2

  公开（公告）日：2017-10-17