(3S)-3,7-diamino-1-naphthalen-1-yl-1-(prop-2-enylamino)heptan-2-one;2,2,2-trifluoroacetic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (3S)-3,7-diamino-1-naphthalen-1-yl-1-(prop-2-enylamino)heptan-2-one;2,2,2-trifluoroacetic acid
• 化学式: C22H28F3N3O3
• 分子量: 439.5
• InChiKey: BTLDBILPQWJNCQ-HMEPSURWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.32
• 重原子数：
  31
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  118
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• [EN] ANTIMICROBIAL COMPOUNDS, THEIR SYNTHESIS AND APPLICATIONS THEREOF<br/>[FR] COMPOSÉS ANTIMICROBIENS, LEUR SYNTHÈSE ET LEURS APPLICATIONS
  申请人：JNCASR BANGALORE

  公开号：WO2014097178A1

  公开（公告）日：2014-06-26

  The present disclosure relates to the field of medicinal chemistry and more particularly to the development of antimicrobial compounds. The disclosure relates to the synthesis and characterization of compounds comprising aromatic radical or an aliphatic radical, an alkyl amine and amino acid moiety wherein said compounds exhibit antimicrobial activity against various drug-sensitive and drug-resistant pathogenic 10 microorganisms.

  本公开涉及药物化学领域，更具体地涉及抗菌化合物的开发。该公开涉及合成和表征包含芳香基团或脂肪基团、烷基胺和氨基酸基团的化合物，其中这些化合物对各种对药物敏感和耐药病原微生物表现出抗菌活性。
• ANTIMICROBIAL COMPOUNDS, THEIR SYNTHESIS AND APPLICATIONS THEREOF
  申请人：JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESARCH

  公开号：US20150329478A1

  公开（公告）日：2015-11-19

  The present disclosure relates to the field of medicinal chemistry and more particularly to the development of antimicrobial compounds. The disclosure relates to the synthesis and characterization of compounds comprising aromatic radical or an aliphatic radical, an alkyl amine and amino acid moiety wherein said compounds exhibit antimicrobial activity against various drug-sensitive and drug-resistant pathogenic 10 microorganisms.

  本公开涉及药物化学领域，更具体地涉及抗微生物化合物的开发。本公开涉及合成和表征包含芳基或脂肪基、烷基胺和氨基酸基团的化合物，其中所述化合物对各种药物敏感和耐药的致病微生物表现出抗微生物活性。
• US9783490B2
  申请人：——

  公开号：US9783490B2

  公开（公告）日：2017-10-10