(2S)-2-methyl-3-[4-(2-oxopropanoylamino)phenyl]propanoic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: (2S)-2-methyl-3-[4-(2-oxopropanoylamino)phenyl]propanoic acid
• 化学式: C₁₃H₁₅NO₄
• 分子量: 249.26
• InChiKey: IOIAUNFZMIQIIP-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  83.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES
  申请人：Ambrx, Inc.

  公开号：US20150094457A1

  公开（公告）日：2015-04-02

  Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typical have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such polypeptides. Typically, the modified non-natural amino acid polypeptides include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Further disclosed are methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses.
• US8791231B2
  申请人：——

  公开号：US8791231B2

  公开（公告）日：2014-07-29
• US8846876B2
  申请人：——

  公开号：US8846876B2

  公开（公告）日：2014-09-30
• US8859802B2
  申请人：——

  公开号：US8859802B2

  公开（公告）日：2014-10-14
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  申请人：——

  公开号：US9637441B2

  公开（公告）日：2017-05-02