3-butyl-2-[(1E,3E,5E)-5-[3-butyl-1,1-dimethyl-6-[methyl-(5-methyl-4-oxohexyl)sulfamoyl]benzo[e]indol-2-ylidene]penta-1,3-dienyl]-1,1-dimethylbenzo[e]indol-3-ium-6,8-disulfonic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-butyl-2-[(1E,3E,5E)-5-[3-butyl-1,1-dimethyl-6-[methyl-(5-methyl-4-oxohexyl)sulfamoyl]benzo[e]indol-2-ylidene]penta-1,3-dienyl]-1,1-dimethylbenzo[e]indol-3-ium-6,8-disulfonic acid
• 化学式: C49H62N3O9S3+
• 分子量: 933.2
• InChiKey: AOOUAOSIHISECT-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  8.9
• 重原子数：
  64
• 可旋转键数：
  18
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  195
• 氢给体数：
  2
• 氢受体数：
  11

文献信息

• Fluorescent Imaging Agents
  申请人：VisEn Medical, Inc.

  公开号：US20170119908A1

  公开（公告）日：2017-05-04

  Provided is a family of intramolecularly quenched imaging agents for use in both in vivo and in vitro imaging that contain at least one enzymatically cleavable oligopeptide and two fluorophores or a fluorophore and a quencher. When subjected to proteolytic cleavage, at least one fluorophore is unquenched and becomes capable of producing a fluorescent signal upon excitation with light of an appropriate wavelength. Also provided are in vivo and in vitro imaging methods using such imaging agents.
• US8815214B2
  申请人：——

  公开号：US8815214B2

  公开（公告）日：2014-08-26
• US9427481B2
  申请人：——

  公开号：US9427481B2

  公开（公告）日：2016-08-30
• US9999687B2
  申请人：——

  公开号：US9999687B2

  公开（公告）日：2018-06-19