11,12-Dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5,8,11-pentaen-4-ol

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 11,12-Dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5,8,11-pentaen-4-ol
• 英文别名: 11,12-dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5,8,11-pentaen-4-ol
• 化学式: C₁₉H₂₃NO
• 分子量: 281.4
• InChiKey: YDEJEHUUIDQRJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• ABUSE RESISTANT CAPSULE
  申请人：R.P. Scherer Technologies, LLC

  公开号：EP2968129A1

  公开（公告）日：2016-01-20
• [EN] ABUSE RESISTANT CAPSULE<br/>[FR] CAPSULE RÉSISTANTE AUX ABUS
  申请人：WENGNER SIMONE

  公开号：WO2014140231A1

  公开（公告）日：2014-09-18

  The present invention is directed to an immediate release and extended release capsule or capsule fill which mitigates the abuse of abuse-susceptible active pharmaceutical ingredients by direct intravenous injection. The fill comprises a parenteral abuse resistant liquid formulation which when mixed with water and heated, results in a turbid, viscous or bubbling mixture that is not injectable with a standard insulin syringe. The abuse-susceptible active pharmaceutical ingredient is selected from the group consisting of opiates, opioids, tranquillizers, stimulants and narcotics.