3',6'-Bis[ethyl(methyl)amino]-3-oxospiro[isoindole-1,9'-xanthene]-2-carboximidamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 3',6'-Bis[ethyl(methyl)amino]-3-oxospiro[isoindole-1,9'-xanthene]-2-carboximidamide
• 英文别名: 3',6'-bis[ethyl(methyl)amino]-3-oxospiro[isoindole-1,9'-xanthene]-2-carboximidamide
• 化学式: C₂₇H₂₉N₅O₂
• 分子量: 455.6
• InChiKey: BKVQCWSQAYQAKE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  34
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  85.9
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] LYSOPHOSPHATIDIC ACID DETECTION<br/>[FR] DÉTECTION D'ACIDE LYSOPHOSPHATIDIQUE
  申请人：OREGON STATE

  公开号：WO2014144561A2

  公开（公告）日：2014-09-18

  Embodiments of methods and compounds for isolating and detecting lysophosphatidic acids (LPAs) are disclosed. Kits for performing the methods also are disclosed. LPAs are isolated from biological samples by liquid-liquid extraction followed by solid phase extraction. LPA species may be separated by HPLC, and the separated species may be identified and quantified. Also disclosed are embodiments of compounds capable of universally detecting a plurality of LPA species with substantially equivalent sensitivity. Embodiments of the disclosed compounds are useful for determination of total LPA concentration in a sample comprising a plurality of LPA species without separation of individual LPA species.