(1R)-1-(5-azido-2-phenyl-1,3-dioxan-4-yl)butan-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二恶烷
• 英文名称: (1R)-1-(5-azido-2-phenyl-1,3-dioxan-4-yl)butan-1-ol
• 化学式: C14H19N3O3
• 分子量: 277.32
• InChiKey: QFEDKOHOVVTNMS-DBBXXEFVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  53
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Glycolipid derivatives, process for production of the same, intermediates for synthesis thereof, and process for production of the intermediates
  申请人：Japan as represented by President of National Center of Neurology and Psychiatry Ministry of Health

  公开号：EP2343306A1

  公开（公告）日：2011-07-13

  Novel glycolipid derivatives, where the substituent of the sphingosine base part is a short carbon chain alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group and efficient synthetic methods for practical mass production of the same and intermediates useful for the synthesis of these compounds. Glycolipids having the formula (I): where R3 indicates a substituted or unsubstituted C1 to C7 linear alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group, or substituted or unsubstituted aralkyl group and R8 indicates a substituted or unsubstituted C1 to C35 alkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group are chemically synthesized.

  新型糖脂衍生物（其中鞘磷脂基部分的取代基为短碳链烷基、取代或未取代的环烷基、取代或未取代的芳基或取代或未取代的芳烷基）以及用于实际大规模生产这些衍生物的高效合成方法和用于合成这些化合物的中间体。 具有式 (I) 的糖脂： 其中 R3 表示取代或未取代的 C1 至 C7 直链烷基、取代或未取代的环烷基、取代或未取代的芳基或取代或未取代的芳烷基，R8 表示取代或未取代的 C1 至 C35 烷基、取代或未取代的芳基或取代或未取代的芳烷基。
• NEW GLYCOLIPIDS AND SYNTHETIC METHOD THEREOF AS WELL AS THEIR SYNTHETIC INTERMEDIATES, AND SYNTHETIC METHOD THEREOF
  申请人：ANNOURA Hirokazu

  公开号：US20100210828A1

  公开（公告）日：2010-08-19

  Novel glycolipid derivatives, where the substituent of the sphingosine base part is a short carbon chain alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group and efficient synthetic methods for practical mass production of the same and intermediates useful for the synthesis of these compounds. Glycolipids having the formula (I): where R 3 indicates a substituted or unsubstituted C 1 to C 7 linear alkyl group, substituted or unsubstituted cycloalkyl group, substituted or unsubstituted aryl group, or substituted or unsubstituted aralkyl group and R 8 indicates a substituted or unsubstituted C 1 to C 35 alkyl group, substituted or unsubstituted aryl group or substituted or unsubstituted aralkyl group are chemically synthesized.
• US7732583B2
  申请人：——

  公开号：US7732583B2

  公开（公告）日：2010-06-08
• US8034908B2
  申请人：——

  公开号：US8034908B2

  公开（公告）日：2011-10-11