methyl 5-methyl-7-vinylbenzofuran-2-carboxylate | 1228276-14-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: methyl 5-methyl-7-vinylbenzofuran-2-carboxylate
• 英文别名: Methyl 7-ethenyl-5-methyl-1-benzofuran-2-carboxylate；methyl 7-ethenyl-5-methyl-1-benzofuran-2-carboxylate
• CAS: 1228276-14-9
• 化学式: C₁₃H₁₂O₃
• 分子量: 216.236
• InChiKey: JCYQMVUEJATVMD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  39.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 、 methyl 5-methyl-7-vinylbenzofuran-2-carboxylate 以0%的产率得到
  参考文献：
  名称：

  New efficient ruthenium metathesis catalyst containing chromenyl ligand

  摘要：

  A synthesis of new Hoveyda-Grubbs-type catalyst with chromenyl ligand was described herein. The new catalyst was tested in model RCM and CM reactions. The catalyst proved to be quite efficient. It showed activity comparable or superior to that of commercially available Grubbs second-generation complexes. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.02.025
• 作为产物：
  描述：

  2-hydroxy-5-methyl-3-vinylbenzaldehyde 、 氯乙酸甲酯 在 四丁基溴化铵 、 potassium carbonate 作用下， 反应 0.67h， 以36%的产率得到methyl 5-methyl-7-vinylbenzofuran-2-carboxylate
  参考文献：
  名称：

  New efficient ruthenium metathesis catalyst containing chromenyl ligand

  摘要：

  A synthesis of new Hoveyda-Grubbs-type catalyst with chromenyl ligand was described herein. The new catalyst was tested in model RCM and CM reactions. The catalyst proved to be quite efficient. It showed activity comparable or superior to that of commercially available Grubbs second-generation complexes. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.02.025

文献信息

• New efficient ruthenium metathesis catalyst containing chromenyl ligand
  作者：Agnieszka Hryniewicka、Jacek W. Morzycki、Stanisław Witkowski

  DOI：10.1016/j.jorganchem.2010.02.025

  日期：2010.5

  A synthesis of new Hoveyda-Grubbs-type catalyst with chromenyl ligand was described herein. The new catalyst was tested in model RCM and CM reactions. The catalyst proved to be quite efficient. It showed activity comparable or superior to that of commercially available Grubbs second-generation complexes. (C) 2010 Elsevier B.V. All rights reserved.