butanedioic acid mono-2-naphthalenyl ester | 71490-68-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: butanedioic acid mono-2-naphthalenyl ester
• 英文别名: succinic acid mono-[2]naphthyl ester；Bernsteinsaeure-mono-[2]naphthylester；4-naphthalen-2-yloxy-4-oxobutanoic acid
• CAS: 71490-68-1
• 化学式: C₁₄H₁₂O₄
• 分子量: 244.247
• InChiKey: OVOAISQTTSURHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-[(2-aminoethyl)amino]-4-oxobutanoic acid 17-oxoandrostan-3-yl ester 、 butanedioic acid mono-2-naphthalenyl ester 在 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 水 、 乙腈 为溶剂， 反应 48.0h， 以55 mg的产率得到4,4'-(1,2-ethanediyldiimino)bis(4-oxobutanoic acid) 1-(2-naphthalenyl) 1'-(17-oxoandrostan-3-yl) ester
  参考文献：
  名称：

  Synthesis and theoretical QSAR study of a naphthalene–androsterone derivative

  摘要：

  A new naphthalene-androsterone derivative was synthesized by the reaction of naphthalenyl succinate with an androsterone-succinate-ethylenediamine conjugate in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide. In order to delineate the structural chemical requirements of naphthalene-androsterone some physicochemical descriptors were evaluated. The results showed an increase in the values of these for the naphthalene-androsterone derivative in comparison with naphthalenyl succinate and androsterone-succinate-ethylenediamine. These data suggest a relationship between the evaluated physicochemical parameters and the degree of lipophilicity of the naphthalene-androsterone derivative.

  DOI：

  10.1007/s00706-011-0584-5
• 作为产物：
  描述：

  丁二酸酐 、 2-萘酚 在 吡啶 作用下， 以 甲苯 为溶剂， 反应 12.0h， 以46 mg的产率得到butanedioic acid mono-2-naphthalenyl ester
  参考文献：
  名称：

  Synthesis and theoretical QSAR study of a naphthalene–androsterone derivative

  摘要：

  A new naphthalene-androsterone derivative was synthesized by the reaction of naphthalenyl succinate with an androsterone-succinate-ethylenediamine conjugate in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide. In order to delineate the structural chemical requirements of naphthalene-androsterone some physicochemical descriptors were evaluated. The results showed an increase in the values of these for the naphthalene-androsterone derivative in comparison with naphthalenyl succinate and androsterone-succinate-ethylenediamine. These data suggest a relationship between the evaluated physicochemical parameters and the degree of lipophilicity of the naphthalene-androsterone derivative.

  DOI：

  10.1007/s00706-011-0584-5

文献信息

• LIQUID CRYSTAL DISPLAY DEVICE
  申请人：DIC Corporation

  公开号：EP3112930A1

  公开（公告）日：2017-01-04

  The present invention provides a liquid crystal display device which can prevent a decrease in a voltage holding ratio (VHR) of a liquid crystal layer and an increase in ion density (ID) and solve a problem of a display defect such as white spots, alignment irregularities, burn-in, or the like. The present invention provides a liquid crystal display device which uses a liquid crystal composition containing a liquid crystal compound having a specific structure as a liquid crystal layer, and an optically anisotropic body obtained by polymerizing a polymerizable liquid crystal composition containing a polymerizable liquid crystal compound having a specific structure at a specific ratio as an in-cell type retardation film. Since the liquid crystal display device of the present invention can prevent a decrease in a voltage holding ratio (VHR) of a liquid crystal layer and an increase in ion density (ID) and suppress the occurrence of a display defect such as burn-in or the like, the liquid crystal display device of the present invention is useful particularly for an active matrix driving VA mode or PSVA mode liquid crystal display device, and can be applied to liquid crystal display devices such as liquid crystal televisions, monitors, mobile phones, smart phones, or the like.

  本发明提供了一种液晶显示装置，它可以防止液晶层的电压保持率（VHR）降低和离子密度（ID）增加，并解决诸如白斑、排列不规则、烧毁等显示缺陷问题。本发明提供了一种液晶显示装置，该装置使用含有具有特定结构的液晶化合物的液晶组合物作为液晶层，并使用通过将含有具有特定结构的可聚合液晶化合物的可聚合液晶组合物按特定比例聚合而得到的光学各向异性体作为单元内型延迟膜。由于本发明的液晶显示装置可防止液晶层的电压保持率（VHR）降低和离子密度（ID）增加，并可抑制显示缺陷（如烧毁等）的发生，因此本发明的液晶显示装置尤其适用于有源矩阵驱动 VA 模式或 PSVA 模式的液晶显示装置，并可应用于液晶电视、显示器、移动电话、智能电话等液晶显示装置。
• Awad et al., Journal of the Chemical Society, 1954, p. 4538,4539, 4540
  作者：Awad et al.

  DOI：——

  日期：——