Methargen | 31055-59-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Methargen
• 英文别名: disilver;3-[(3-sulfonatonaphthalen-2-yl)methyl]naphthalene-2-sulfonate
• CAS: 31055-59-1；53370-43-7
• 化学式: C21H14Ag2O6S2
• 分子量: 642.2
• InChiKey: BROSRFATIJCNNM-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  3.39
• 重原子数：
  31
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  131
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Haemostatic Compositions
  申请人：Nozotec AB

  公开号：EP1972339A1

  公开（公告）日：2008-09-24

  The invention relates to a composition comprising: (a) one or more aminoacids selected from glycine, proline and hydroxyproline; (b) a source of calcium ions; and (c) water. The invention also extends to a dry composition comprising the aforementioned components (a) and (b). The compositions of the invention are useful for arresting bleeding of humans and other animals, in particular for accelerating haemostasis at the site of incisions made during surgical procedures.

  本发明涉及一种包含以下成分的组合物：(a) 选自甘氨酸、脯氨酸和羟脯氨酸的一种或 多种氨基酸；(b) 钙离子源；以及 (c) 水。本发明还包括一种由上述成分（a）和（b）组成的干燥组合物。本发明的组合物可用于止住人类和其他动物的出血，特别是用于加速外科手术切口处的止血。
• COMPOSITION FOR COMBATING EPISTAXIS
  申请人：Pharmacure Health Care AB

  公开号：EP2117502B1

  公开（公告）日：2016-11-09
• HAEMOSTATIC COMPOSITION AND METHOD
  申请人：Petruson Bjorn

  公开号：US20080233176A1

  公开（公告）日：2008-09-25

  The invention relates to a composition comprising: (a) one or more aminoacids selected from glycine, proline and hydroxyproline; (b) a source of calcium ions; and (c) water. The invention also extends to a dry composition comprising the aforementioned components (a) and (b). The compositions of the invention are useful for arresting bleeding of humans and other animals, in particular for accelerating haemostasis at the site of incisions made during surgical procedures.
• US9138406B2
  申请人：——

  公开号：US9138406B2

  公开（公告）日：2015-09-22
• [EN] COMPOSITION FOR COMBATING EPISTAXIS<br/>[FR] COMPOSITION POUR LUTTER CONTRE L'ÉPISTAXIS
  申请人：PHARMACURE HEALTH CARE AB

  公开号：WO2008102150A2

  公开（公告）日：2008-08-28

  [EN] The invention relates to a gel composition comprising: a) a carboxy polymethylene polymer; b) glycine; c) a source of calcium ions; and d) water. The invention also extends to a dry composition comprising the aforementioned components a), b) and c). The gel compositions of the invention are useful for the prophylaxis and treatment of epistaxis. The gel compositions can be easily administered to the nasal cavity and do not require removal after use.
  [FR] L'invention concerne une composition sous forme de gel, comprenant: a) un polymère de carboxypolyméthylène; b) de la glycine; ) une source d'ions calcium; et d) de l'eau. L'invention concerne également une composition sèche comprenant les composants a), b) et c) ci-dessus. Les compositions sous forme de gel de l'invention sont utiles pour la prévention et le traitement de l'épistaxis. Les compositions sous forme de gel peuvent être facilement administrées dans la fosse nasale et ne doivent pas être éliminées après leur utilisation.