1,5-Naphthalenedisulfonicacid, 3-isothiocyanato- | 74220-99-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,5-Naphthalenedisulfonicacid, 3-isothiocyanato-
• 英文别名: 3-isothiocyanatonaphthalene-1,5-disulfonic acid
• CAS: 74220-99-8
• 化学式: C₁₁H₇NO₆S₃
• 分子量: 345.4
• InChiKey: VBNBCMZEYBETOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  170
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• Pyrenyloxysulfonic acid fluorescent agents
  申请人：Haugland Richard

  公开号：US20050123935A1

  公开（公告）日：2005-06-09

  The invention provides a novel class of reactive fluorescent agents that are based on a pyrene sulfonic acid nucleus. The agents are readily incorporated into conjugates with other species by reacting the reactive group with a group of complementary reactivity on the other species of the conjugate. Also provided are methods of using the compounds of the invention to detect and/or quantify an analyte in a sample. In an exemplary embodiment, the invention provides multi-color assays incorporating the compounds of the invention.

  本发明提供了一类基于芘磺酸核的新型活性荧光剂。通过使活性基团与共轭物中其他物质上具有互补反应性的基团反应，这些制剂很容易与其他物质结合成共轭物。此外，还提供了使用本发明化合物检测和/或量化样品中分析物的方法。在一个示例性实施方案中，本发明提供了包含本发明化合物的多色检测方法。
• PYRENYLOXYSULFONIC ACID FLURESCENT AGENTS
  申请人：Haugland Richard

  公开号：US20080032379A1

  公开（公告）日：2008-02-07

  The invention provides a novel class of reactive fluorescent agents that are based on a pyrene sulfonic acid nucleus. The agents are readily incorporated into conjugates with other species by reacting the reactive group with a group of complementary reactivity on the other species of the conjugate. Also provided are methods of using the compounds of the invention to detect and/or quantify an analyte in a sample. In an exemplary embodiment, the invention provides multi-color assays incorporating the compounds of the invention.
• PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS
  申请人：Haugland Richard

  公开号：US20120045848A1

  公开（公告）日：2012-02-23

  The invention provides a novel class of reactive fluorescent agents that are based on a pyrene sulfonic acid nucleus. The agents are readily incorporated into conjugates with other species by reacting the reactive group with a group of complementary reactivity on the other species of the conjugate. Also provided are methods of using the compounds of the invention to detect and/or quantify an analyte in a sample. In an exemplary embodiment, the invention provides multi-color assays incorporating the compounds of the invention.
• US5132432A
  申请人：——

  公开号：US5132432A

  公开（公告）日：1992-07-21
• US8039642B2
  申请人：——

  公开号：US8039642B2

  公开（公告）日：2011-10-18