6-aminobenzonorbornadiene | 35391-95-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 6-aminobenzonorbornadiene
• 英文别名: 3-Aminobenzonorbornadien；6-Aminobenzonorbornadien；6-amino-1,4-methano-1,4-dihydro-naphthalene；1,4-Methanonaphthalene-6-amine, 1,4-dihydro-；tricyclo[6.2.1.02,7]undeca-2(7),3,5,9-tetraen-4-amine
• CAS: 35391-95-8
• 化学式: C₁₁H₁₁N
• 分子量: 157.215
• InChiKey: IVJVBCKECSDPQU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Process for the production of amines
  申请人：Syngenta Participations AG

  公开号：EP2014642A1

  公开（公告）日：2009-01-14

  The present invention relates to a process for the preparation of compounds of formula I wherein R1 is C6-C7alkyl or a group A1 wherein R2, R3 and R4 are each independently of the others hydrogen or C1-C4alkyl; wherein a compound of formula II wherein R1 is as defined for formula I and X is bromine or chlorine, is reacted with urea in the presence of a base and a catalytic amount of at least one palladium complex compound, wherein the palladium complex compound comprises at least one ferrocenyl-biphosphine ligand.

  本发明涉及一种制备I式化合物的方法，其中R1为C6-C7烷基或A1基团，R2、R3和R4各自独立地为氢或C1-C4烷基；其中，II式化合物（其中R1如I式定义，X为溴或氯）在碱和至少一种钯配合物催化剂的存在下与尿素反应，所述钯配合物包括至少一种二茂铁双膦配体。
• PROCESS FOR THE PRODUCTION OF AROMATIC AMINDES IN THE PRESENCE OF A PALLADIUM COMPLEX COMPRISING A FERROCENYL BIPHOSPHINE LIGAND
  申请人：Walter Harald

  公开号：US20100256417A1

  公开（公告）日：2010-10-07

  The present invention relates to a process for the preparation of compounds of Formula (I), wherein R 1 is 1,3-dimethyl-butyl, 1,3,3-trimethyl-butyl or a group A 1 , wherein R 3 , R 4 and R 5 are each independently of the others hydrogen or C 1 -C 4 alkyl; and R 2 is hydrogen; or R 1 and R 2 together from the group A 2 , wherein R 6 , and R7 are each independently of the other hydrogen or C 1 -C 4 alkyl; or R 1 and R 2 together from the group A 3 , wherein R 5 and R 9 are each independently of the other hydrogen or C 1 -C 4 alkyl; wherein a compound of Formula (II) wherein R 1 and R 2 are as defined for formula I and X is bromine or chlorine, is reacted with ammonia in the presence of a base and a catalytic amount of at least one palladium complex compound, wherein the palladium complex compound comprises at least one ferrocenyl-biphosphine ligand.

  本发明涉及一种制备式（I）化合物的方法，其中R1为1,3-二甲基丁基、1,3,3-三甲基丁基或A1基团，其中R3、R4和R5各自独立地为氢或C1-C4烷基；R2为氢；或者R1和R2一起形成A2基团，其中R6和R7各自独立地为氢或C1-C4烷基；或者R1和R2一起形成A3基团，其中R5和R9各自独立地为氢或C1-C4烷基；其中化合物式（II）其中R1和R2如式（I）所定义，X为溴或氯，在碱和至少一种钯配合物催化剂的存在下与氨反应，其中钯配合物包括至少一种二茂铁双膦配体。
• PROCESS FOR THE PRODUCTION OF AROMATIC AMINES IN THE PRESENCE OF A PALLADIUM COMPLEX COMPRISING A FERROCENYL BIPHOSPHINE LIGAND
  申请人：Syngenta Participations AG

  公开号：EP2066617A1

  公开（公告）日：2009-06-10
• [EN] PROCESS FOR THE PRODUCTION OF AROMATIC AMINES IN THE PRESENCE OF A PALLADIUM COMPLEX COMPRISING A FERROCENYL BIPHOSPHINE LIGAND<br/>[FR] PROCÉDÉ DE PRODUCTION D'AMINES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2008017443A1

  公开（公告）日：2008-02-14

  [EN] The present invention relates to a process for the preparation of compounds of Formula (I), wherein R₁ is 1,3-dimethyl-butyl, 1,3,3-trimethyl-butyl or a group A₁, wherein R₃, R₄ and R₅ are each independently of the others hydrogen or C₁-C₄alkyl; and R₂ is hydrogen; or R₁ and R₂ together from the group A₂, wherein R₆ and R7 are each independently of the other hydrogen or C₁-C₄alkyl; or R₁ and R₂ together from the group A₃, wherein R₈ and R₉ are each independently of the other hydrogen or C₁-C₄alkyl; wherein a compound of Formula (II) wherein R₁ and R₂ are as defined for formula I and X is bromine or chlorine, is reacted with ammonia in the presence of a base and a catalytic amount of at least one palladium complex compound, wherein the palladium complex compound comprises at least one ferrocenyl-biphosphine ligand.
  [FR] La présente invention concerne un procédé de préparation de composés de formule I (I), dans laquelle : R₁ est un groupe 1,3-diméthylbutyle, un groupe 1,3,3-triméthylbutyle ou un groupe A₁ dans lequel R₃, R₄ et R₅ sont chacun indépendamment des atomes d'hydrogène ou un alkyle en C₁ à C₄, et R₂ est un atome d'hydrogène; ou bien R₁ et R₂ forment ensemble le groupe A₂, dans lequel R₆ et R₇ sont chacun indépendamment des atomes d'hydrogène ou un alkyle en C₁ à C₄; ou bien R₁ et R₂ forment ensemble le groupe A₃, dans lequel R₈ et R₉ sont chacun indépendamment des atomes d'hydrogène ou un alkyle en C₁ à C₄. Le procédé de l'invention implique de faire réagir un composé de formule II (II) (dans laquelle R₁ et R₂ sont tels que définis pour la formule I et X représente un atome de brome ou de chlore) avec de l'ammoniaque en présence d'une base et d'une quantité catalytique d'au moins un complexe du palladium, ledit complexe comprenant au moins un ligand ferrocényle-biphosphine.