Desoxymorellin | 1064-34-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: Desoxymorellin
• 英文别名: (2S)-12-hydroxy-8,8,21,21-tetramethyl-5,19-bis(3-methylbut-2-enyl)-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,9,11,15-pentaene-14,18-dione
• CAS: 1064-34-2
• 化学式: C₃₃H₃₈O₆
• 分子量: 530.661
• InChiKey: VZQQLPACAVHZQT-RNLYVTMESA-N

物化性质

• 熔点：
  113-115 °C(Solv: hexane (110-54-3))
• 沸点：
  695.4±55.0 °C(Predicted)
• 密度：
  1.27±0.1 g/cm3(Predicted)
• 溶解度：
  溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  39
• 可旋转键数：
  4
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  82.1
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Fractionated products obtained from gamboge resin, and medical uses of the same
  申请人：Lee Sen-Bin

  公开号：US20110305784A1

  公开（公告）日：2011-12-15

  Disclosed herein are seventeen new compounds and five fractionated products obtained from an acetone-extracted product of gamboge resin. The seventeen new compounds and the five fractionated products have activities in inhibiting the growth of tumor/cancer cells. In addition, the acetone-extracted product of gamboge resin and the five fractionated products obtained therefrom have analgesic and anti-inflammatory effects.
• Novel compound obtained from gamboge resin, and medical uses of the same
  申请人：Lee Sen-Bin

  公开号：US20110306658A1

  公开（公告）日：2011-12-15

  Disclosed herein are seventeen new compounds obtained from an acetone-extracted product of gamboge resin. The seventeen new compounds have activities in inhibiting the growth of tumor/cancer cells.
• USE OF FRACTIONATED PRODUCTS OF GAMBOGE RESIN IN THE TREATMENT OF CANCER, PAIN, AND INFLAMMATION
  申请人：Lee Sen-Bin

  公开号：US20160089357A1

  公开（公告）日：2016-03-31

  Disclosed herein are seventeen new compounds and five fractionated products obtained from an acetone-extracted product of gamboge resin. The seventeen new compounds and the five fractionated products have activities in inhibiting the growth of tumor/cancer cells. In addition, the acetone-extracted product of gamboge resin and the five fractionated products obtained therefrom have analgesic and anti-inflammatory effects.
• NOVEL COMPOUND OBTAINED FROM GAMBOGE RESIN, AND MEDICAL USES OF THE SAME
  申请人：Taiwan Sunpan Biotechnology Development Co., Ltd.

  公开号：US20160338991A1

  公开（公告）日：2016-11-24

  Disclosed herein are seventeen new compounds obtained from an acetone-extracted product of gamboge resin. The seventeen new compounds have activities in inhibiting the growth of tumor/cancer cells.
• US9498463B2
  申请人：——

  公开号：US9498463B2

  公开（公告）日：2016-11-22