1-Naphthyl isocyanide

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-Naphthyl isocyanide
• 英文别名: methylidyne(naphthalen-1-yl)azanium
• 化学式: C11H8N+
• 分子量: 154.19
• InChiKey: PYBZXADBZLKEOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  4.4
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• Inhibitor of Apoptosis Protein (IAP) Antagonists
  申请人：Sanford-Burnham Medical Research Institute

  公开号：US20170081362A1

  公开（公告）日：2017-03-23

  Provided herein are compounds that modulate the activity of inhibitor of apoptosis proteins (IAPB), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.
• [EN] INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS<br/>[FR] ANTAGONISTES DES PROTÉINES INHIBITRICES DE L'APOPTOSE (IAPS)
  申请人：SANFORD BURNHAM MED RES INST

  公开号：WO2014085489A1

  公开（公告）日：2014-06-05

  Provided herein are compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.
• [EN] USE OF INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS IN HIV THERAPY<br/>[FR] UTILISATION D'UN INHIBITEUR DES ANTAGONISTES DE LA PROTÉINE D'APOPTOSE (IAP) DANS UNE THÉRAPIE CONTRE LE VIH
  申请人：SANFORD BURNHAM MED RES INST

  公开号：WO2015187998A2

  公开（公告）日：2015-12-10

  Provided herein is the use of compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), alone or in combination with other therapeutic agents, in the treatment of human immunodeficiency virus (HIV).