6H-Dibenzo(b,d)pyran-1,9,10-triol, 7,8,9,10-tetrahydro-6,6,9-trimethyl-3-pentyl-, trans- | 74184-29-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 6H-Dibenzo(b,d)pyran-1,9,10-triol, 7,8,9,10-tetrahydro-6,6,9-trimethyl-3-pentyl-, trans-
• 英文别名: (9S,10S)-6,6,9-trimethyl-3-pentyl-8,10-dihydro-7H-benzo[c]chromene-1,9,10-triol
• CAS: 74184-29-5
• 化学式: C₂₁H₃₀O₄
• 分子量: 346.5
• InChiKey: ZLYNXDIDWUWASO-FPOVZHCZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  69.9
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Cannabinoid composition and products including α-tocopherol
  申请人：Constance Therapeutics, Inc.

  公开号：US10238745B2

  公开（公告）日：2019-03-26

  A cannabinoid composition having an excipient including α-tocopherol and at least one isolated cannabinoid having a purity of greater than 80%. The α-tocopherol inhibits oxidation, regulates viscosity of the composition, and improves bioavailability of the cannabinoid. The composition includes a carrier oil mixed with the excipient and cannabinoid. In one embodiment, the at least one cannabinoid is an isolated cannabinoid having a greater than 80% purity, and preferably greater than 90% purity. The at least one cannabinoid is selected from the group consisting of phytocannabinoids, endocannabinoids, synthetic cannabinoids, and combinations thereof. The cannabinoid may be derived from plants other than cannabis sativa, or synthesized from fungi, bacteria, yeast or other synthetic method. Preferably the α-tocopherol comprises at least 10% w/w of the composition.

  一种大麻素组合物，其赋形剂包括α-生育酚和至少一种纯度大于 80% 的分离大麻素。α-生育酚可抑制氧化，调节组合物的粘度，提高大麻素的生物利用度。组合物包括与赋形剂和大麻素混合的载体油。在一个实施方案中，至少一种大麻素是分离出来的大麻素，纯度大于 80%，最好大于 90%。至少一种大麻素选自植物大麻素、内源性大麻素、合成大麻素及其组合组成的组。大麻素可以从大麻以外的植物中提取，也可以从真菌、细菌、酵母或其他合成方法中合成。α-生育酚最好至少占组合物重量的 10%。
• Cannabis oil extracts and compositions
  申请人：CONSTANCE THERAPEUTICS, INC.

  公开号：US10406186B2

  公开（公告）日：2019-09-10

  The present invention provides cannabis oil extracts and compositions thereof, including cannabis oil compositions containing vitamin E, and methods for preparing the extracts and compositions. In some embodiments, the present invention provides a method for preparing a cannabis oil extract comprising eluting cannabinoids from cannabis plant material with a solvent to produce an eluate, filtering the eluate with a filter to produce a filtrate, evaporating the solvent from the filtrate with a distiller to produce a distillate, and purging the distillate under conditions sufficient to remove residual solvent, thereby preparing the extract. In some embodiments, the method further includes mixing a quantity of vitamin E with the extract to produce a cannabis oil composition.

  本发明提供了大麻油提取物及其组合物，包括含有维生素 E 的大麻油组合物，以及制备提取物和组合物的方法。在一些实施方案中，本发明提供了一种制备大麻油提取物的方法，包括用溶剂从大麻植物材料中洗脱大麻素以产生洗脱液，用过滤器过滤洗脱液以产生滤液，用蒸馏器蒸发滤液中的溶剂以产生蒸馏物，在足以除去残留溶剂的条件下净化蒸馏物，从而制备提取物。在某些实施方案中，该方法还包括将一定量的维生素 E 与萃取物混合，制成大麻油组合物。
• Breeding, production, processing and use of medical cannabis
  申请人：BIOTECH INSTITUTE, LLC

  公开号：US10441617B2

  公开（公告）日：2019-10-15

  The invention provides compositions and methods for the breeding, production, processing and use of medical cannabis.

  本发明提供了用于培育、生产、加工和使用医用大麻的组合物和方法。
• Cannabis oil compositions and methods for preparation thereof
  申请人：Constance Therapeutics, Inc.

  公开号：US10806707B2

  公开（公告）日：2020-10-20

  The present invention provides cannabis oil compositions, including cannabis oil compositions containing vitamin E, and methods for preparing the cannabis oil compositions. In some embodiments, the invention provides a method for preparing a cannabis oil composition comprising eluting cannabinoids from cannabis plant material with a solvent to produce an eluate; filtering the eluate with a filter to produce a filtrate; evaporating the solvent from the filtrate with a distiller to produce a distillate; and purging the distillate under conditions sufficient to remove residual solvent. In some embodiments, the method further includes mixing a quantity of vitamin E with the extract. Blended cannabis oil compositions containing mixtures of cannabis oil preparations are also described.

  本发明提供了大麻油组合物，包括含有维生素 E 的大麻油组合物，以及制备大 麻油组合物的方法。在一些实施例中，本发明提供了一种制备大麻油组合物的方法，包括用溶剂从大麻植物材料中洗脱大麻素以产生洗脱液；用过滤器过滤洗脱液以产生滤液；用蒸馏器蒸发滤液中的溶剂以产生蒸馏物；以及在足以去除残留溶剂的条件下净化蒸馏物。在某些实施方案中，该方法还包括将一定量的维生素 E 与萃取物混合。还描述了含有大麻油制剂混合物的混合大麻油组合物。
• Apparatus and methods for sample analysis and classification based on terpenes and cannabinoids in the sample
  申请人：Biotech Institute, LLC

  公开号：US10830780B2

  公开（公告）日：2020-11-10

  The disclosure relates to systems, apparatuses, and methods for estimating a terpene level of two or more terpenes of the plurality of terpenes in the sample to generate a set of terpene levels; and/or estimating a cannabinoid level of two or more cannabinoids of the plurality of cannabinoids in the sample to generate a set of cannabinoid levels; configured to store a set of groups and classify the sample to a group of the set of groups, based on said terpene and cannabinoid levels. The present disclosure also relates to systems, apparatuses, and methods configured to generate entourage effect values and organoleptic values, based on said cannabinoid and terpene levels.

  本公开涉及系统、装置和方法，用于估算样品中多种萜烯中两种或多种萜烯的萜烯含量，以生成一组萜烯含量；和/或估算样品中多种大麻素中两种或多种大麻素的大麻素含量，以生成一组大麻素含量；根据所述萜烯和大麻素含量，配置为存储一组组别并将样品分类到组别中的一组。本公开还涉及根据所述大麻素和萜烯含量生成随附效应值和感官值的系统、装置和方法。