9H-Xanthene-9-thiol | 89562-30-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 9H-Xanthene-9-thiol
• CAS: 89562-30-1
• 化学式: C₁₃H₁₀OS
• 分子量: 214.28
• InChiKey: BCZADNSFSRFPNJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  10.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Oleic acid esters and pharmaceutical compositions
  申请人：H. LUNDBECK A/S

  公开号：EP0270282A2

  公开（公告）日：1988-06-08

  The invention relates to oleic acid esters of the Formula R O - - (CH₂)₇ CH = CH (CH₂)₇ CH₃      I wherein R is as defined in Claim 1, and to said esters as active ingredients in long acting injectable pharmaceutical compositions. A method for the preparation of said esters is also described.

  本发明涉及式 R O - - (CH₂)₇ CH = CH (CH₂)₇ CH₃ I 的油酸酯，其中 R 如权利要求 1 所定义，还涉及作为长效注射药物组合物活性成分的所述酯。 本发明还描述了制备所述酯的方法。
• Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor
  申请人：Millennium Pharmaceuticals, Inc.

  公开号：US20020103111A1

  公开（公告）日：2002-08-01

  The present invention provides novel compounds comprising peptide sequences which mimic the conserved amino acid motif LDTSL of MAdCAM-1 and which have groups bonded to the N- and C-termini. Also provided are methods of inhibiting the interaction of a cell bearing a ligand of MAdCAM-1, such as human &agr;4&bgr;7, with MAdCAM-1 or a portion thereof (e.g., the extracellular domain), comprising contacting the cell with a compound of the present invention.

  本发明提供了包含肽序列的新型化合物，这些肽序列模拟 MAdCAM-1 的保守氨基酸基序 LDTSL，并在 N 端和 C 端键合有基团。本发明还提供了抑制带有 MAdCAM-1 配体（如人 &agr;4&bgr;7）的细胞与 MAdCAM-1 或其部分（如胞外结构域）相互作用的方法，包括使细胞与本发明的化合物接触。
• Photopolymerizable composition
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0563925B1

  公开（公告）日：2000-02-02
• EP0871670A2
  申请人：——

  公开号：EP0871670A2

  公开（公告）日：1998-10-21
• VISIBLE LIGHT CURING SYSTEMS, METHODS FOR REDUCING HEALTH RISKS TO INDIVIDUALS EXPOSED TO SYSTEMS DESIGNED TO CURE CURABLE COMPOSITIONS BY EXPOSURE TO RADIATION, METHODS FOR BONDING SUBSTRATES AND VISIBLE LIGHT CURING COMPOSITIONS
  申请人：Henkel Corporation

  公开号：EP1971427A1

  公开（公告）日：2008-09-24