4,4'-bis-(2,4-dimethoxy-benzoylamino)-trans-stilbene-2,2'-disulfonic acid | 25807-07-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 4,4'-bis-(2,4-dimethoxy-benzoylamino)-trans-stilbene-2,2'-disulfonic acid
• 英文别名: 4,4'-Bis-(2,4-dimethoxy-benzoylamino)-trans-stilben-2,2'-disulfonsaeure；5-[(2,4-dimethoxybenzoyl)amino]-2-[(E)-2-[4-[(2,4-dimethoxybenzoyl)amino]-2-sulfophenyl]ethenyl]benzenesulfonic acid
• CAS: 25807-07-2
• 化学式: C₃₂H₃₀N₂O₁₂S₂
• 分子量: 698.728
• InChiKey: KWERBAWTHMJUHY-AATRIKPKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  48
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  221
• 氢给体数：
  4
• 氢受体数：
  12

文献信息

• HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES WITH VISUALIZATION MOIETY
  申请人：SURMODICS, INC.

  公开号：US20130261566A1

  公开（公告）日：2013-10-03

  The invention is directed to medical device coatings, such as coated guidewires and catheters, containing a visualization moiety providing color to the coating in ambient or applied light. The coating allows for visual or machine inspection of coating properties such as uniformity of coverage. In some embodiments the coatings include the visualization moiety and an activated UV photogroup, which is used to provide covalent bonding in the coating. The visualization moiety can be in particulate form and entrained in the coating, or can be covalently bonded to the hydrophilic polymer backbone. In other embodiments the visualization moiety includes a stilbene chemical group. Exemplary coatings include a hydrophilic vinyl pyrrolidone polymer, which can provide lubricity to the device surface, along with the colored properties.
• US8956682B2
  申请人：——

  公开号：US8956682B2

  公开（公告）日：2015-02-17
• [EN] HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES WITH VISUALIZATION MOIETY<br/>[FR] REVÊTEMENTS POLYMÈRES HYDROPHILES POUR DES ARTICLES MÉDICAUX AYANT UNE FRACTION DE VISUALISATION
  申请人：SURMODICS INC

  公开号：WO2013151991A1

  公开（公告）日：2013-10-10

  The invention is directed to medical device coatings, such as coated guidewires and catheters, containing a visualization moiety providing color to the coating in ambient or applied light. The coating allows for visual or machine inspection of coating properties such as uniformity of coverage. In some embodiments the coatings include the visualization moiety and an activated UV photogroup, which is used to provide covalent bonding in the coating. The visualization moiety can be in particulate form and entrained in the coating, or can be covalently bonded to the hydrophilic polymer backbone. In other embodiments the visualization moiety includes a stilbene chemical group. Exemplary coatings include a hydrophilic vinyl pyrrolidone polymer, which can provide lubricity to the device surface, along with the colored properties.