2-(2-Hydroxyethyl)naphthalene-1,4-dione | 55700-12-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(2-Hydroxyethyl)naphthalene-1,4-dione
• CAS: 55700-12-4
• 化学式: C₁₂H₁₀O₃
• 分子量: 202.21
• InChiKey: CJAYFZCIFCQFBQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Composition, element and method using polymeric mordants to increase the intensity of rigid fluorescent dyes
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0231127A2

  公开（公告）日：1987-08-05

  Cationic and anionic polymeric mordants are used with rigid phenalenone, benzphenalenone or 4-oxo-4H-benz-[d,e]-anthracene fluorescent dyes or precursors thereof to increase fluorescence intensity. Compositions and analytical elements containing the mordants and dyes or dye precursors are useful in biological studies, such as cell and tissue staining and cell cytometry, and in analytical determinations for various analytes, e.g. living organisms.

  阳离子和阴离子聚合物媒染剂可与硬质苯丙酮、苯并芘或 4-氧代-4H-苯并-[d,e]-蒽荧光染料或其前体一起使用，以增加荧光强度。含有媒染剂和染料或染料前体的组合物和分析元件可用于生物研究，如细胞和组织染色和细胞计数，以及各种分析物（如生物体）的分析测定。
• Biological and analytical uses of phenalenone and benzphenalenone compounds
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0232130A2

  公开（公告）日：1987-08-12

  Certain phenalenone and benzphenalenone fluorescent compounds are useful in biomedical studies and analytical determinations. These compounds are particularly useful in assays for living organisms. for example microorganisms, carried out at a pH of 9 or less For these determinations, the compounds can be attached to reducible compounds which will subsequently release the fluorescent moiety upon reduction. In the presence of an electron transfer agent. the reducible compounds are easily reduced by a microorganism.

  某些苯茚酮和苯并芘荧光化合物可用于生物医学研究和分析测定。 这些化合物特别适用于在 pH 值为 9 或更低的条件下对生物体（例如微生物）进行检测。 在有电子转移剂存在的情况下，可还原化合物很容易被微生物还原。
• Fluorescent dyes and biological and analytical uses thereof
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0231126A2

  公开（公告）日：1987-08-05

  Substituted 4-oxo-4H-benz-[d,e]anthracenes are fluorescent dyes which are useful in biomedical studies and analytical determinations. They are particularly useful in assays for living organisms, for example, microorganisms, carried out at a pH of 9 or less. For these determinations, the fluorescent dyes can be attached to reducible compounds which will release the dye upon reduction. Alternatively, these dyes can be used in assays for hydrolytic enzymes or biological cells containing these enzymes. For these determinations, the dyes are attached to blocking groups.

  取代的 4-氧代-4H-苯并-[d,e]蒽是一种荧光染料，可用于生物医学研究和分析测定。 它们特别适用于在 pH 值为 9 或更低的条件下对生物体（例如微生物）进行测定。 在进行这些测定时，荧光染料可附着在可还原的化合物上，这些化合物在还原时会释放染料。 另外，这些染料还可用于水解酶或含有这些酶的生物细胞的测定。 在进行这些测定时，染料可附着在阻断基团上。
• Rapid differentiation of fungi from bacteria using polyene antibiotics
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0261931A2

  公开（公告）日：1988-03-30

  Rapid differentiation between viable fungi (for example, yeast) and viable bacteria is accomp­lished with certain polyene antibiotics which are used in combination with a compound which is normally reducible by both the fungi and the bacteria. The antibiotics selectively and substantially inhibit the reduction of the reducible compound by the fungi but do not affect the reducing capacity of the bacteria. The particular antibiotics useful are polyenes which selectively affect the function of the cytoplasmic membrane of fungi.

  某些多烯抗生素与真菌和细菌通常都能还原的化合物结合使用，可以快速区分有生命力的真菌（例如酵母）和有生命力的细菌。抗生素选择性地、实质性地抑制真菌还原可还原化合物，但不影响细菌的还原能力。特别有用的抗生素是选择性影响真菌细胞质膜功能的多烯类抗生素。
• Rapid differentiation of bacteria using polyether antibiotics
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0261933A2

  公开（公告）日：1988-03-30

  Rapid differentiation between viable gram-­positive and gram-negative bacteria is accomplished with polyether antibiotics which are used in combina­tion with a compound which is normally reducible by the bacteria. The antibiotics selectively and sub­stantially inhibit the reduction of the reducible compound by gram-positive bacteria but do not sub­stantially affect the reducing capacity of the gram-­negative bacteria.

  聚醚抗生素与细菌通常可还原的化合物结合使用，可快速区分存活的革兰氏阳性菌和革兰氏阴性菌。抗生素可选择性地大量抑制革兰氏阳性细菌还原可还原化合物，但不会大量影响革兰氏阴性细菌的还原能力。