7H-1-Benzopyran-7-one | 239783-62-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 7H-1-Benzopyran-7-one
• 英文别名: chromen-7-one
• CAS: 239783-62-1
• 化学式: C₉H₆O₂
• 分子量: 146.14
• InChiKey: VJBCBLLQDMITLJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• SYNTHESIS OF MORIN AND MORIN DERIVATIVES
  申请人：ORSATEC GMBH

  公开号：US20200308131A1

  公开（公告）日：2020-10-01

  The invention relates to a method for directly producing morin derivatives and high-purity morin of formula (I). The invention also relates to morin derivatives and high-purity morin that can be obtained using the claimed method.

  该发明涉及一种直接生产公式（I）的槲皮素衍生物和高纯度槲皮素的方法。该发明还涉及可以使用所述方法获得的槲皮素衍生物和高纯度槲皮素。
• SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF
  申请人：THE REGENTS OF THE UNIVERSITY OF MICHIGAN

  公开号：US20150284387A1

  公开（公告）日：2015-10-08

  This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having pyrazolopyridine structure which function as inhibitors of Mcl-1 protein, and their use as therapeutics for the treatment of cancer and other diseases.

  这项发明属于药物化学领域。具体来说，该发明涉及一类具有吡唑吡啶结构的新型小分子，其作为Mcl-1蛋白抑制剂的功能，以及它们作为治疗癌症和其他疾病的药物的用途。
• COMPOSITIONS AND METHODS FOR PROTECTING CELLS FROM TOXIC EXPOSURES
  申请人：Thomas James P.

  公开号：US20080253997A1

  公开（公告）日：2008-10-16

  The present invention provides compositions and methods for protecting cells and tissues from damage associated with therapeutic treatments of cancers and other diseases and conditions where reactive oxygen species are produced. The present invention also provides compositions useful as research reagents.

  本发明提供了一种组合物和方法，用于保护细胞和组织免受治疗癌症和其他疾病和情况（其中产生反应性氧化物种）所引起的损伤。本发明还提供了作为研究试剂的有用组合物。
• SMALL MOLECULE INHIBITORS OF MCL-1 AND THE USES OF THEREOF
  申请人：WAYNE STATE UNIVERSITY

  公开号：US20140235702A1

  公开（公告）日：2014-08-21

  This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having sulfonamido-1-hydroxynaphthalene structure which function as inhibitors of Mcl-1 protein, and their use as therapeutics for the treatment of cancer and other diseases.

  这项发明涉及药物化学领域。具体而言，该发明涉及一类新型小分子，具有磺酰胺基-1-羟基萘结构，可作为Mcl-1蛋白酶抑制剂，并可用作治疗癌症和其他疾病的治疗剂。
• FMO3 inhibitors for treating pain
  申请人：Akron Molecules GmbH

  公开号：EP2674161A1

  公开（公告）日：2013-12-18

  The present invention relates to new therapies to treat pain and related diseases, as well as pharmaceutical compounds for use in said therapies.

  本发明涉及治疗疼痛和相关疾病的新疗法，以及用于上述疗法的药物化合物。