3-(Naphthalen-2-yloxy)azetidine | 784123-27-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-(Naphthalen-2-yloxy)azetidine
• 英文别名: 3-naphthalen-2-yloxyazetidine
• CAS: 784123-27-9
• 化学式: C₁₃H₁₃NO
• 分子量: 199.25
• InChiKey: ZQXUEIDHHHQAEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险等级：
  IRRITANT

文献信息

• Cyclic Ureas
  申请人：SIRONAX LTD

  公开号：US20210292305A1

  公开（公告）日：2021-09-23

  The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.