Fluoreno[1,2-b]pyran | 126967-71-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: Fluoreno[1,2-b]pyran
• 英文别名: indeno[1,2-h]chromene
• CAS: 126967-71-3
• 化学式: C₁₆H₁₀O
• 分子量: 218.25
• InChiKey: OOEAIXLASGCZOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• N-Substituted Indenoisoquinolines and Syntheses Thereof
  申请人：Cushman Mark S.

  公开号：US20080318995A1

  公开（公告）日：2008-12-25

  N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted indenoisoquinoline compounds. Also described are methods for treating cancer in mammals using the described N-substituted indenoisoquinoline compounds or pharmaceutical formulations thereof.

  本发明涉及N-取代的茚并异喹啉化合物及其制备方法，以及N-取代的茚并异喹啉化合物的药物制剂。同时，还描述了制备N-取代的茚并异喹啉化合物的方法。本发明还涉及使用所述的N-取代的茚并异喹啉化合物或其药物制剂治疗哺乳动物癌症的方法。
• N-substituted indenoisoquinolines and syntheses thereof
  申请人：Cushman Mark S.

  公开号：US20120101119A1

  公开（公告）日：2012-04-26

  N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted indenoisoquinoline compounds. Also described are methods for treating cancer in mammals using the described N-substituted indenoisoquinoline compounds or pharmaceutical formulations thereof.

  本发明涉及N-取代吲哚异喹啉化合物及其药物制剂。还描述了制备N-取代吲哚异喹啉化合物的过程。还描述了使用所述N-取代吲哚异喹啉化合物或其药物制剂治疗哺乳动物癌症的方法。
• N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF
  申请人：CUSHMAN Mark S.

  公开号：US20140336188A1

  公开（公告）日：2014-11-13

  N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted indenoisoquinoline compounds. Also described are methods for treating cancer in mammals using the described N-substituted indenoisoquinoline compounds or pharmaceutical formulations thereof.

  本文描述了N-取代吲哚异喹啉化合物及其药物配方，并描述了制备N-取代吲哚异喹啉化合物的过程。同时，本文还描述了使用所述N-取代吲哚异喹啉化合物或其药物配方治疗哺乳动物癌症的方法。
• A PROCESS FOR PREPARING N-SUBSTITUTED INDENOISOQUINOLINES
  申请人：Purdue Research Foundation

  公开号：EP3112349A2

  公开（公告）日：2017-01-04

  A process for preparing a compound of the formula without isolating an intermediate product, the process comprising: reacting a compound of the formula with a compound of the formula and cyclizing the intermediate product.

  一种制备式化合物的工艺 不分离中间产物的制备方法，该方法包括 与一种式化合物反应 和 环化中间产物。
• Photochromic pyran compounds
  申请人：——

  公开号：US20020169315A1

  公开（公告）日：2002-11-14

  Photochromic pyran compounds and their use in synthetic resin objects of all types, especially for ophthalmic applications, particularly spiro compounds having a fluorene structure derived from naphthopyrans, which are known as spirofluorenopyrans. By introducing respectively only one strongly electron donating or withdrawing group at specific positions in the periphery of the pyran dye, photochromic compounds obtained which in the excited state are distinguished by an expanded color spectrum, while simulataneously offering comparably good bleaching rates and good durability.

  光致变色吡喃化合物及其在各类合成树脂物体中的应用，特别是在眼科应用中的应用，尤其是具有从萘并吡喃衍生而来的芴结构的螺并化合物，这种化合物被称为螺芴并吡喃。通过在吡喃染料外围的特定位置分别只引入一个强电子供体或析出基团，可获得光致变色化合物，这种化合物在激发态下具有扩展的色谱，同时具有相当好的漂白率和良好的耐久性。