6-Methyl-1H,2H,3H-pyrrolo[3,2-B]pyridine | 1256808-17-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯并吡啶类
• 英文名称: 6-Methyl-1H,2H,3H-pyrrolo[3,2-B]pyridine
• 英文别名: 6-methyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine
• CAS: 1256808-17-9
• 化学式: C₈H₁₀N₂
• 分子量: 134.18
• InChiKey: RYLATXGLBCLUBM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  24.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• NEW PROPANAMINE DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS
  申请人：ESTEVE PHARMACEUTICALS, S.A.

  公开号：US20200207759A1

  公开（公告）日：2020-07-02

  The present invention relates to new compounds of general formula (I) that show dual activity towards α2δ subunit of voltage-gated calcium channels (VGCC), especially the α2δ-1 subunit, and to the noradrenallne transporter (NET). The invention is also related to the process for the preparation of said compounds as well as to compositions comprising them, and to their use as medicaments.