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(3E)-3-[(5-chloro-2-hydroxyphenyl)hydrazinylidene]-5-hydroxy-4-oxonaphthalene-2,7-disulfonic acid

中文名称
——
中文别名
——
英文名称
(3E)-3-[(5-chloro-2-hydroxyphenyl)hydrazinylidene]-5-hydroxy-4-oxonaphthalene-2,7-disulfonic acid
英文别名
——
(3E)-3-[(5-chloro-2-hydroxyphenyl)hydrazinylidene]-5-hydroxy-4-oxonaphthalene-2,7-disulfonic acid化学式
CAS
——
化学式
C16H11ClN2O9S2
mdl
——
分子量
474.9
InChiKey
UPDNHPLARLKXAI-CYVLTUHYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    1.8
  • 重原子数:
    30
  • 可旋转键数:
    4
  • 环数:
    3.0
  • sp3杂化的碳原子比例:
    0.0
  • 拓扑面积:
    207
  • 氢给体数:
    5
  • 氢受体数:
    11

文献信息

  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCERS AND PATHOGENIC INFECTIONS
    申请人:Dunn William A.
    公开号:US20120141491A1
    公开(公告)日:2012-06-07
    The subject application provides small compounds that are able to increase/enhance autophagy in various cells. These compounds are useful in augmenting existing treatments of various cancers, microbial/viral infections, and neurodegenerative diseases. Thus, the subject application also provides methods of treating various types of cancers, microbial/viral infections, and neurodegenerative diseases.
  • [EN] METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCERS AND PATHOGENIC INFECTIONS<br/>[FR] MÉTHODES ET COMPOSITIONS POUVANT ÊTRE UTILISÉES DANS LE CADRE DU TRAITEMENT DES CANCERS ET DES INFECTIONS PATHOGÈNES
    申请人:UNIV FLORIDA
    公开号:WO2011019636A2
    公开(公告)日:2011-02-17
    The subject application provides small compounds that are able to increase/enhance autophagy in various cells. These compounds are useful in augmenting existing treatments of various cancers, microbial/viral infections, and neurodegenerative diseases. Thus, the subject application also provides methods of treating various types of cancers, microbial/viral infections, and neurodegenerative diseases.
  • [EN] AUTOPHAGY-INDUCING MOLECULES FOR INCREASING INSULIN RELEASE<br/>[FR] MOLÉCULES INDUISANT UNE AUTOPHAGIE PERMETTANT D'AUGMENTER LA LIBÉRATION D'INSULINE
    申请人:UNIV STRASBOURG
    公开号:WO2016119856A1
    公开(公告)日:2016-08-04
    The present invention relates to the use of autophagy-inducing molecules for increasing release or secretion of insulin by pancreatic β cells. It is useful for treating hyperglycemia, associated or not with diabetes.
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