1,2,3,4,5,7,8,9-Octahydropyrido[1,2-a][1,4]diazepine | 105014-11-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂卓
• 英文名称: 1,2,3,4,5,7,8,9-Octahydropyrido[1,2-a][1,4]diazepine
• CAS: 105014-11-7
• 化学式: C₉H₁₆N₂
• 分子量: 152.24
• InChiKey: HYNDYAQJODYUGF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES
  申请人：Stierli Daniel

  公开号：US20130072535A1

  公开（公告）日：2013-03-21

  Compounds of Formula (I) wherein R 1 is C 1 -C 4 alkyl or C 1 -C 4 haloalkyl; R 2 is C 1 -C 4 alkyl; R 3 is hydrogen or halogen; R 4 is hydrogen, C 1 -C 4 alkyl or C 1 -C 4 halogenalkyl; R 5 is hydrogen, halogen, C 1 -C 4 alkyl or C 1 -C 4 halogenalkyl; R 6 is hydrogen, halogen, C 1 -C 4 alkyl, C 2 -C 6 alkenyl or C 3 -C 6 alkinyl; R 7 is hydrogen, halogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 3 -C 6 alkinyl, C 3 -C 6 cycloalkyl-C 3 -C 6 alkinyl, halophenoxy, halophenyi, C 1 -C 6 haloalkyl, C 1 -C 6 haloakoxy, C 2 -C 6 haloalkenyl, or C 2 -C 6 haloalkenyloxy; R 8 is hydrogen, halogen, C 1 -C 4 alkyl, C 2 -C 6 alkenyl or C 3 -C 6 alkinyl; with the provisio that at least one of R 6 , R 7 and R 8 is different from hydrogen; n is 0 or 1, are suitable for use as microbriocides.

  公式(I)的化合物，其中R1是C1-C4烷基或C1-C4卤代烷基；R2是C1-C4烷基；R3是氢或卤素；R4是氢，C1-C4烷基或C1-C4卤代烷基；R5是氢，卤素，C1-C4烷基或C1-C4卤代烷基；R6是氢，卤素，C1-C4烷基，C2-C6烯基或C3-C6炔基；R7是氢，卤素，C1-C6烷基，C2-C6烯基，C3-C6炔基，C3-C6环烷基-C3-C6炔基，卤代苯氧基，卤代苯基，C1-C6卤代烷基，C1-C6卤代烷氧基，C2-C6卤代烯基或C2-C6卤代烯氧基；R8是氢，卤素，C1-C4烷基，C2-C6烯基或C3-C6炔基；前提是R6、R7和R8中至少有一个不同于氢；n是0或1，适用于作为微生物杀灭剂的用途。
• 4-AMINO-7,8-DIHYDROPYRIDO[4,3-d]PYRIMIDIN-5(6H)-ONE DERIVATIVES
  申请人：Aspnes Gary E.

  公开号：US20100197591A1

  公开（公告）日：2010-08-05

  The invention provides compounds of the general Formula (I) where R 1 , R 2 , and A are defined herein, as well as the preparation, compositions and uses thereof.

  这项发明提供了一般式（I）的化合物 其中R1、R2和A在此处定义，以及其制备、组成和用途。
• Method for Preparing Nanoparticles Based on Functional Amphiphilic Molecules or Macromolecules, and the Use Thereof
  申请人：Barthelemy Philippe

  公开号：US20110059180A1

  公开（公告）日：2011-03-10

  The invention relates to a method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, optionally in the presence of at least one colipide, enabling the encapsulation of therapeutic agents, especially anti-tumoral agents, and the use thereof for the transport and vectorisation of therapeutic agents, especially anti-tumoral agents.

  这项发明涉及一种基于功能性两性分子或大分子制备纳米颗粒的方法，可选地在至少一种胆固醇类物质的存在下，使治疗剂，特别是抗肿瘤剂的封装成为可能，并且用于运输和载体化治疗剂，特别是抗肿瘤剂。
• Substituted pyridine herbicides
  申请人：——

  公开号：US20030040437A1

  公开（公告）日：2003-02-27

  1 Compounds of formula (I), in which the substituents are as defined in claim 1 and the agrochemically tolerated salts M+ and all stereoisomers and tautomers of the compounds of formula (I) are suitable for use as herbicides.

  式（I）化合物，其中取代基如权利要求1中定义的那样，以及农药中可容忍的盐M+和式（I）化合物的所有立体异构体和互变异构体均适用于用作除草剂。
• [EN] PHENOXYPROPENYLPHENYL DERIVATIVES AND THEIR USE AS HERBICIDES<br/>[FR] DERIVES DE PHENOXYPROPENYLPHENYL ET LEUR UTILISATION EN TANT QU'HERBICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2004002947A1

  公开（公告）日：2004-01-08

  Compounds of formula (I), wherein R01 is hydrogen, C1-C8alkyl, C3-C8alkenyl or C3-C8alkynyl; or R01 is phenyl or phenyl-C1-C6alkyl, it being possible for the phenyl rings in turn to be mono- to penta-substituted by halogen and/or mono-, di- or tri-substituted by C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, -CN, -NO2, C1-C8alkylthio, C1-C8alkylsulfinyl or C1-C8alkylsulfonyl; or R01 is C1-C8alkyl mono- to penta-substituted by halogen or mono-, di- or tri-substituted by -CN, C1-C6alkylamino, di(C1-C6alkyl)amino or C1-C4alkoxy; n is 0, 1, 2, 3 or 4; each R1 independently is halogen, -CN, -SCN, -SF5, -NO2, -NH2, -C02R7, -CONR8R9, -C(S)NH2, -C(R10)=NOR11, -COR12, -OR13, -SR14, -SOR15, -SO2R16, -OSO2R17, C1-C8alkyl, C2-C8alkenyl, C2-C8alkynyl or C3-C6cycloalkyl; or C1-C8alkyl, C2-C8alkenyl or C2-C8alkynyl mono- to penta-substituted by halogen and/or mono-, di- or tri-substituted by -CN, -NO2, -NR18R19, -CO2R20, -CONR21R22, -COR23, -C(R24)=NOR25, -C(S)NR26R27, -C(C1-C4alkylthio)=NR28, -OR29, -SR30, -SOR31, -SO2R32 or C3-C6cycloalkyl; and/or each R1 independently is C3-C6cycloalkyl mono- to penta-substituted by halogen and/or mono-, di- or tri-substituted by -CN, -NO2, -NR18R19, -CO2R20, -CONR21R22, -COR23, -C(R24)=NOR25, -C(S)NR26R27, -C(C1-C4alkylthio)=NR28, -SR30, -SOR31, -SO2R32 or C3C6cycloalkyl; and/or each R1 independently is phenyl, which in turn can be mono- to penta-substituted by halogen and/or mono-, di- or tri-substituted by C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, -CN, -NO2, C1-C4alkylthio, C1-C4alkylsulfinyl or C1-C4alkylsulfonyl; and/or two adjacent R1 together form a C1-C7alkylene bridge, which can be interrupted by from 1 to 3 hetero atoms selected from oxygen, nitrogen and sulfur and which can be mono- to penta-substituted by halogen and/or mono-, di- or tri-substituted by C1-C6alkyl or C1-C6alkoxy, the total number of ring atoms being at least 5 and at most 9; and/or two adjacent R1 together form a C2-C7alkenylene bridge, which can be interrupted by from 1 to 3 hetero atoms selected from oxygen, nitrogen and sulfur and which can be mono- to penta-substituted by halogen and/or mono-, di- or tri-substituted by C1-C6alkyl or C1-C6alkoxy, the total number of ring atoms being at least 5 and at most 9; R3 and R4 are each independently of the other hydrogen, halogen, -CN, C1-C4alkyl or C1-C4alkoxy; or R3 and R4 together are C2-C5alkylene; m is 1, 2, 3, 4 or 5; and R2, R7 to R32, X1 and X2 are as defined in claim 1, and the agrochemically acceptable salts, N-oxides and all stereoisomers and tautomers of the compounds of formula (I) are suitable for use as herbicides.

  式(I)的化合物，其中R01是氢，C1-C8烷基，C3-C8烯基或C3-C8炔基；或者R01是苯基或苯基-C1-C6烷基，苯环可能被卤素单取代至五取代，或者单、二或三取代为C1-C4烷基，C1-C4卤代烷基，C1-C4烷氧基，-CN，-NO2，C1-C8烷基硫醚，C1-C8烷基磺醇或C1-C8烷基磺酰基；或者R01是被卤素单取代至五取代或单、二或三取代为-CN，C1-C6烷基胺基，二(C1-C6烷基)胺基或C1-C4烷氧基的C1-C8烷基；n为0、1、2、3或4；每个R1独立地是卤素，-CN，-SCN，-SF5，-NO2，-NH2，-C02R7，-CONR8R9，-C(S)NH2，-C(R10)=NOR11，-COR12，-OR13，-SR14，-SOR15，-SO2R16，-OSO2R17，C1-C8烷基，C2-C8烯基，C2-C8炔基或C3-C6环烷基；或者C1-C8烷基，C2-C8烯基或C2-C8炔基被卤素单取代至五取代，或者单、二或三取代为-CN，-NO2，-NR18R19，-CO2R20，-CONR21R22，-COR23，-C(R24)=NOR25，-C(S)NR26R27，-C(C1-C4烷基硫)=NR28，-OR29，-SR30，-SOR31，-SO2R32或C3-C6环烷基；和/或每个R1独立地被卤素单取代至五取代，或者单、二或三取代为-CN，-NO2，-NR18R19，-CO2R20，-CONR21R22，-COR23，-C(R24)=NOR25，-C(S)NR26R27，-C(C1-C4烷基硫)=NR28，-SR30，-SOR31，-SO2R32或C3C6环烷基；和/或每个R1独立地是苯基，苯基可以被卤素单取代至五取代，或者单、二或三取代为C1-C4烷基，C1-C4卤代烷基，C1-C4烷氧基，-CN，-NO2，C1-C4烷基硫醚，C1-C4烷基磺醇或C1-C4烷基磺酰基；和/或两个相邻的R1一起形成C1-C7烷基桥，可以被由氧、氮和硫选择的1至3个杂原子中断，并且可以被卤素单取代至五取代，或者单、二或三取代为C1-C6烷基或C1-C6烷氧基，环原子总数至少为5且至多为9；和/或两个相邻的R1一起形成C2-C7烯基桥，可以被由氧、氮和硫选择的1至3个杂原子中断，并且可以被卤素单取代至五取代，或者单、二或三取代为C1-C6烷基或C1-C6烷氧基，环原子总数至少为5且至多为9；R3和R4分别独立地为氢，卤素，-CN，C1-C4烷基或C1-C4烷氧基；或者R3和R4一起为C2-C5烷基；m为1、2、3、4或5；R2、R7到R32、X1和X2如权利要求1中定义，化合物的所有立体异构体和互变异构体以及式(I)的农药可接受盐和N-氧化物适用于作为除草剂。