4-[(E)-1-[4-[2-(diethylamino)ethoxy]phenyl]prop-1-en-2-yl]phenol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 4-[(E)-1-[4-[2-(diethylamino)ethoxy]phenyl]prop-1-en-2-yl]phenol
• 化学式: C₂₁H₂₇NO₂
• 分子量: 325.4
• InChiKey: QHBKYHFJPWWUKM-WUKNDPDISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  24
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  32.7
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NOVEL FUNCTIONALIZED N,N-DIALKYLAMINO PHENYL ETHERS AND THEIR METHOD OF USE
  申请人：Temple University-Of The Commonwealth System of Higher Education

  公开号：US20200392073A1

  公开（公告）日：2020-12-17

  Pharmaceutical compositions of the invention comprise functionalized N,N-dialkylamino phenyl ethers derivatives having a disease-modifying action in the treatment of diseases associated with lysosomal storage dysfunction that include Gaucher's disease, and any disease or condition involving lysosomal storage dysfunction.