3-(3-isobutoxyphenyl)propanoic acid | 1057602-15-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 3-(3-isobutoxyphenyl)propanoic acid
• 英文别名: 3-(2-Methylpropoxy)benzenepropanoic acid；3-[3-(2-methylpropoxy)phenyl]propanoic acid
• CAS: 1057602-15-9
• 化学式: C₁₃H₁₈O₃
• 分子量: 222.284
• InChiKey: NPMWJRMKDHLMEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS
  申请人：Gschneidner David

  公开号：US20110046050A1

  公开（公告）日：2011-02-24

  The present invention provides phenylalkylcarboxylic acid compounds and compositions containing such compounds which facilitate the delivery of biologically active agents.

  本发明提供苯基烷基羧酸化合物及含有此类化合物的组合物，有助于传递生物活性物质。
• Phenylalkylcarboxylic acid delivery agents
  申请人：Emisphere Technologies, Inc.

  公开号：US10456472B2

  公开（公告）日：2019-10-29

  The present invention provides phenylalkylcarboxylic acid compounds and compositions containing such compounds which facilitate the delivery of biologically active agents.

  本发明提供了苯基烷基羧酸化合物和含有此类化合物的组合物，它们有助于生物活性剂的递送。
• COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE
  申请人：Urigen Pharmaceuticals, Inc.

  公开号：EP3110427A1

  公开（公告）日：2017-01-04
• COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS
  申请人：PARSONS C. Lowell

  公开号：US20170189443A1

  公开（公告）日：2017-07-06

  The present invention is directed to a pharmaceutical composition comprising: (1) a therapeutically effective quantity of sodium pentosan polysulfate; (2) a quantity of a penetration enhancer sufficient to improve the bioavailability of the sodium pentosan polysulfate; and (3) optionally, a pharmaceutically acceptable carrier and to methods for the oral administration of sodium pentosan polysulfate with improved bioavailability for the treatment of interstitial cystitis and other urinary tract diseases and conditions. Such compositions and methods allow the administration of sodium pentosan polysulfate at lower dosages to reduce the frequency and severity of side effects.
• [EN] PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS<br/>[FR] AGENTS DE DISTRIBUTION D'ACIDE PHÉNYLALKYLCARBOXYLIQUE
  申请人：EMISPHERE TECH INC

  公开号：WO2008112368A2

  公开（公告）日：2008-09-18

  [EN] The present invention provides phenylalkylcarboxylic acid compounds and compositions containing such compounds which facilitate the delivery of biologically active agents.
  [FR] L'invention concerne des composés acide phénylalkylcarboxylique et des compositions contenant de tels composés qui facilitent la distribution d'agents biologiquement actifs.