1-chloro-trans-3,4-dibutylaluminocyclopentane

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机过渡后金属化合物
• 英文名称: 1-chloro-trans-3,4-dibutylaluminocyclopentane
• 英文别名: (3S,4S)-3,4-dibutyl-1-chloroalumolane
• 化学式: C₁₂H₂₄AlCl
• 分子量: 230.757
• InChiKey: YWPPEDZZRBOFGY-AQEKLAMFSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  4.84
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  三氯化铝 、 1-己烯 在 二氯二茂锆 magnesium 作用下， 以 四氢呋喃 为溶剂， 生成 1-chloro-trans-3,4-dibutylaluminocyclopentane
  参考文献：
  名称：

  新型有机铝化合物的取代基和立体选择性合成-取代的氧化铝环戊烷和氧化铝环戊烯

  摘要：

  A novel regio- and stereoselective method has been developed for the catalytic cyclometallation of olefins and acetylenes with alkylalanes in the presence of Cp(2)ZrCl(2), to give in one stage high yields of 3-substituted aluminacyclopentanes and aluminacyclopentenes. Applications of these reactions to a wide range of linear and cyclic olefins and to those containing functional substituents have been studied. The transformation of the aluminacyclopentanes thus produced, into five-membered heterocycles, mono- and di-substituted cyclobutanes and cyclopropanes, has been demonstrated.

  DOI：

  10.1016/0022-328x(94)88022-0

文献信息

• Synthesis and transformations of metallocycles. 9. Regioselective and stereoselective synthesis of al-substitutedtrans-3,4-dialkylaluminocyclopentanes catalyzed by (?5-C5H5)2ZrCl2
  作者：U. M. Dzhemilev、A. G. Ibragimov、A. B. Morozov、R. R. Muslukhov、G. A. Tolstikov

  DOI：10.1007/bf00866593

  日期：1992.6

  A new stereoselective method is developed for the synthesis of 1-chloro-, 1-alkoxy-, and 1-N,N-dialkylaminoalumino-cyclopentanes from alpha-olefins, metallic magnesium, and aluminum halides (AlCl3, RO-AlCl2, R2N-AlCl2) in the presence of catalytic amounts of Cp2ZrCl2 (Cp = eta5-C5H5). The products from hydrolysis and deuterolysis of the Al-substituted 3,4-dialkylaluminocyclopentanes (ACP) have the threo configuration.
• Regio- and stereoselective synthesis for a novel class of organoaluminium compounds — substituted aluminacyclopentanes and aluminacyclopentenes assis
  作者：U.M. Dzhemilev、A.G. Ibragimov

  DOI：10.1016/0022-328x(94)88022-0

  日期：1994.2

  A novel regio- and stereoselective method has been developed for the catalytic cyclometallation of olefins and acetylenes with alkylalanes in the presence of Cp(2)ZrCl(2), to give in one stage high yields of 3-substituted aluminacyclopentanes and aluminacyclopentenes. Applications of these reactions to a wide range of linear and cyclic olefins and to those containing functional substituents have been studied. The transformation of the aluminacyclopentanes thus produced, into five-membered heterocycles, mono- and di-substituted cyclobutanes and cyclopropanes, has been demonstrated.