烯丙基三(3,3,4,4,5,5,6,6,7,7,8,8,8-十三氟辛基)锡烷

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机过渡后金属化合物
• 中文名称: 烯丙基三(3,3,4,4,5,5,6,6,7,7,8,8,8-十三氟辛基)锡烷
• 中文别名: 烯丙基三(1H,1H,2H,2H-全氟辛基)锡烷；三(1H,1H,2H,2H-全氟辛基)烯丙基锡
• 英文名称: allyltris(1H,1H,2H,2H-perfluorooctyl)stannane
• 化学式: C₂₇H₁₇F₃₉Sn
• 分子量: 1201.08
• InChiKey: RMDIHFFKXXTNGQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.01
• 重原子数：
  67
• 可旋转键数：
  23
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  39

反应信息

• 作为反应物：
  描述：

  烯丙基三(3,3,4,4,5,5,6,6,7,7,8,8,8-十三氟辛基)锡烷 、 环己烷基甲醛 反应 72.0h， 以80%的产率得到1-环己基-3-丁烯-1-醇
  参考文献：
  名称：

  Thermal Allylations of Aldehydes with a Fluorous Allylstannane. Separation of Organic and Fluorous Products by Solid Phase Extraction with Fluorous Reverse Phase Silica Gel

  摘要：

  DOI：

  10.1021/jo9710590

文献信息

• Rapid Fluorous Stille Coupling Reactions Conducted under Microwave Irradiation
  作者：Mats Larhed、Masahide Hoshino、Sabine Hadida、Dennis P. Curran、Anders Hallberg

  DOI：10.1021/jo970362y

  日期：1997.8.1

  Palladium-catalyzed fluorous Stille cross-coupling reactions with organic halides or triflates require only 90-120 s for completion when conducted under microwave irradiation. Comparable thermal reactions require about 1 day. Fourteen different coupling products were synthesized and isolated in good yields after three-phase extraction (FC-84, dichloromethane, water) and chromatography. The examples extend the scope of the fluorous Stille coupling with respect to both the tin and halide/triflate components. Applications in parallel synthesis are suggested.
• Thermal Allylations of Aldehydes with a Fluorous Allylstannane. Separation of Organic and Fluorous Products by Solid Phase Extraction with Fluorous Reverse Phase Silica Gel
  作者：Dennis P. Curran、Sabine Hadida、Mu He

  DOI：10.1021/jo9710590

  日期：1997.10.1