二甲氧基甲基氯硅烷 | 994-07-0

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 中文名称: 二甲氧基甲基氯硅烷
• 英文名称: chlorodimethoxymethylsilane
• 英文别名: methyldimethoxychlorosilane；dimethoxymethylsilyl chloride；chloro-dimethoxy-methylsilane
• CAS: 994-07-0
• 化学式: C₃H₉ClO₂Si
• 分子量: 140.642
• InChiKey: GYQKYMDXABOCBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.09
• 重原子数：
  7
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2931900090
• 储存条件：
  2-8°C

反应信息

• 作为反应物：
  描述：

  二甲氧基甲基氯硅烷 在 tetrakis(diphenylmethoxy)silane 、 吡啶 作用下， 以 乙腈 、 甲醇 为溶剂， 反应 3.0h， 以1.8 g的产率得到Tetrakis[dimethoxy(methyl)silyl] silicate
  参考文献：
  名称：

  Direct alkoxysilylation of alkoxysilanes for the synthesis of explicit alkoxysiloxane oligomers

  摘要：

  Direct alkoxysilylation, which is a powerful tool to provide explicit alkoxysiloxanes, is developed and its versatility is investigated. Siloxane pentamers Si[OSiR1(OMe)(2)](4) having various functional groups (R-1 = methyl, vinyl, phenyl, chloropropyl and n-butyl groups) were successfully obtained by direct alkoxysilylation of Si(OR)(4) (R= t-Bu, CHPh2). Thus, the versatility of the reaction is confirmed on organic functional groups R-1. Functional group tolerance of the reaction is discussed on the basis of electro-negativity of the R-1 groups. Alkoxysilylation of Si(Ot-Bu)(2)(OMe)(2) and Si(Ot-Bu)(OMe)(3) selectively gives trimer (MeO)(2)Si[OSiMe(OMe)(2)](2) and dimer (MeO)(3)SiOSiMe(OMe)(2), respectively. Thus, the feasibility on siloxane structure is also confirmed. Various siloxane compounds are synthesized by this newly developed reaction for the first time. (C) 2012 Published by Elsevier B.V.

  DOI：

  10.1016/j.jorganchem.2012.05.033
• 作为产物：
  描述：

  dimethoxy(phenyl)silane 在 四氯化碳 、 palladium dichloride 作用下， 以 苯 为溶剂， 以9.78 g的产率得到二甲氧基甲基氯硅烷
  参考文献：
  名称：

  邻（二氢甲硅烷基）（二甲磺基）苯的合成与结构

  摘要：

  以6个步骤制备O-（二氢甲硅烷基）（二甲磺基）苯1。邻-二溴苯与正丁基锂单片化，并与氯（二甲氧基）硅烷反应，得到邻-C 6 H 4（Br）[SiR（OMe）2 ]（2）（R = Ph，Me）。溴-锂在2和叔丁基锂之间的交换产生了o -C 6 H 4（Li）[SiR（OMe）2 ]（3），将其与氟硼烷（dimesityl ）硼烷反应生成o -C 6 H 4（BMes）2）[SiR（OMe）2 ]（4）。用LiAlH 4在THF中还原4得到[ o -C 6 H 4（BMes 2 H）（SiRH 2）] - Li +（thf）n（9）。用BF 3 OEt 2处理9得到目标化合物1。1的结构通过NMR光谱和X射线晶体学分析确定。

  DOI：

  10.1016/j.jorganchem.2010.06.007

文献信息

• Über siliciumschwefel-verbindungen
  作者：Dietmar Brandes

  DOI：10.1016/s0022-328x(00)87963-2

  日期：1977.8

  Novel organylthio(alkoxy)silanes (I, II, III and XII) and organylthio(diethylamino)silanes (IV, V) are described. They were prepared by treating lithium or lead thiolates with the corresponding chlorosilanes or by cleavage of dimethylbis(diethylamino)silane with thiols. Phenylthiosilanes (Me3SiSPh, III and XIII) furthermore can be obtained by reaction of chlorosilanes with benzenethiol in the presence

  描述了新型有机硫基（烷氧基）硅烷（I，II，III和XII）和有机硫基（二乙基氨基）硅烷（IV，V）。它们是通过用相应的氯硅烷处理锂或硫醇铅制得的，或通过用硫醇裂解二甲基双（二乙氨基）硅烷来制备的。苯硫基硅烷（Me 3 SiSPh，III和XIII）还可以通过在叔胺存在下使氯硅烷与苯硫醇反应来获得。Me 3 SiSPh的SiS键被诸如Me 2 Si（NEt 2）Cl或Me 2 Si（OPr）Cl的氯硅烷裂解。该反应是制备化合物I和IV的便利途径。研究了新型化合物的物理和化学性质。
• Protecting and Leaving Functions of Trimethylsilyl Groups in Trimethylsilylated Silicates for the Synthesis of Alkoxysiloxane Oligomers
  作者：Masashi Yoshikawa、Yasuhiro Tamura、Ryutaro Wakabayashi、Misa Tamai、Atsushi Shimojima、Kazuyuki Kuroda

  DOI：10.1002/anie.201705942

  日期：2017.11.6

  The concept of protecting groups in organic synthesis is applied to the synthesis of siloxane oligomers with alkoxy groups. Several alkoxysiloxane oligomers were successfully synthesized by substitution of trimethysilyl groups with alkoxysilyl groups.

  有机合成中的保护基团的概念适用于具有烷氧基的硅氧烷低聚物的合成。通过用烷氧基甲硅烷基取代三甲基甲硅烷基，成功地合成了几种烷氧基硅氧烷低聚物。
• Enantioselective CuH-Catalyzed Hydroacylation Employing Unsaturated Carboxylic Acids as Aldehyde Surrogates
  作者：Yujing Zhou、Jeffrey S. Bandar、Stephen L. Buchwald

  DOI：10.1021/jacs.7b04937

  日期：2017.6.21

  (CuH)-catalyzed coupling of α,β-unsaturated carboxylic acids to aryl alkenes to access chiral α-aryl dialkyl ketones is reported. A variety of substrate substitution patterns, sensitive functional groups, and heterocycles are tolerated in this reaction, which significantly expands the range of accessible products compared with existing hydroacylation methodology. Although mechanistic studies are ongoing, we propose

  报道了直接不对称氢化铜（CuH）催化的α，β-不饱和羧酸与芳基烯烃的偶联，从而获得手性α-芳基二烷基酮。在该反应中可以耐受多种底物取代方式，敏感的官能团和杂环，与现有的加氢酰化方法相比，这大大扩展了可及产品的范围。尽管正在进行机理研究，但我们建议发生CuH催化的不饱和酸甲硅烷基化反应，以访问独特有效的酰基亲电偶联伙伴。
• The effect of methyl substitution on the electronic structure of bis(dimethyl ether) pentadienyllithium
  作者：John F. Sebastian、Bennett Hsu、John R. Grunwell

  DOI：10.1016/s0022-328x(00)91966-1

  日期：1976.1

  ether) pentadienyllithium has been calculated by the CNDO/2 method. The metal—anion interaction involves both σ and π bonding. The effect of methyl Substitution on the electronic structure of the solvated species has been evaluated. In general, the electronic effect of a methyl group is substantially less for the solvated structure than for the isolated anion.

  双（二甲醚）戊二烯基锂的部分几何优化结构已通过CNDO / 2方法进行了计算。金属-阴离子相互作用涉及σ键和π键。已经评估了甲基取代对溶剂化物质电子结构的影响。通常，对于溶剂化的结构，甲基的电子效应明显小于对分离的阴离子的甲基的电子效应。
• Arylaminosilane Compound, Propylene Polymerization Catalyst And Preparation Thereof
  申请人：PetroChina Company Limited

  公开号：US20200369689A1

  公开（公告）日：2020-11-26

  The present disclosure discloses an arylaminosilane compound, a propylene polymerization catalyst and preparation thereof. The arylaminosilane compound has a structure of wherein R 1 is a C 1 -C 8 alkyl group or a C 1 -C 8 silanyl group; R 2 , R 3 , R 4 , R 5 and R 6 are each independently H or a C 1 -C 12 alkyl group; R 7 , R 8 and R 9 are each independently a C 1 -C 8 alkyl group or a C 1 -C 8 alkoxy group. When the arylaminosilane compound is used as an external electron donor of a propylene polymerization catalyst in propylene polymerization reaction, the catalyst has good hydrogen response.

  本公开揭示了一种芳基氨基硅烷化合物、丙烯聚合催化剂及其制备方法。该芳基氨基硅烷化合物的结构为其中R1是C1-C8烷基或C1-C8硅烷基；R2、R3、R4、R5和R6分别独立地为H或C1-C12烷基；R7、R8和R9分别独立地为C1-C8烷基或C1-C8烷氧基。当该芳基氨基硅烷化合物作为丙烯聚合催化剂的外部电子受体在丙烯聚合反应中使用时，催化剂具有良好的氢响应。