isopropyl 2,2,3,3-tetrafluoropropylcarbonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: isopropyl 2,2,3,3-tetrafluoropropylcarbonate
• 英文别名: Isopropyl 2,2,3,3-tetrafluoropropyl carbonate；propan-2-yl 2,2,3,3-tetrafluoropropyl carbonate
• 化学式: C₇H₁₀F₄O₃
• 分子量: 218.148
• InChiKey: OVIKCIBOASSNLJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  2,2,3,3-tetrafluoropropyl chloroformate 、 异丙醇 生成 isopropyl 2,2,3,3-tetrafluoropropylcarbonate
  参考文献：
  名称：

  Orlov, S. I.; Chimishkyan, A. L.; Elinevskii, A. V., Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, # 3, p. 417 - 420

  摘要：

  DOI：

文献信息

• Phosgene-free synthesis of symmetric bis(polyfluoroalkyl) carbonates
  作者：Anna M. Semenova、Marina A. Ezhikova、Mikhail I. Kodess、Aleksandr Ya. Zapevalov、Aleksandr V. Pestov

  DOI：10.1016/j.mencom.2021.03.038

  日期：2021.3

  A phosgene-free synthesis of symmetric bis(polyfluoroalkyl) carbonates involves the transesterification of diphenyl carbonate with polyfluoroalkanols promoted by stoichiometric amounts of titanium(iv) alkoxides.

  对称性碳酸二（聚氟代烷基）酯的无光气合成涉及碳酸二苯酯与化学计量的钛（iv）烷氧基化物促进的聚氟代烷醇的酯交换反应。
• New Synthetic Approach to Polyfluorinated Carbonates
  作者：A. M. Semenova、M. A. Ezhikova、M. I. Kodess、A. Ya. Zapevalov、A. V. Pestov

  DOI：10.1134/s1070428020040120

  日期：2020.4

  Transesterification of commercial titanium(IV) alkoxides with 2,2,3,3-tetrafluoropropan-1-ol, followed by in situ transesterification of mixed titanium(IV) alkoxides thus formed with diphenyl carbonate, afforded alkyl 2,2,3,3-tetrafluoropropyl carbonates and bis(2,2,3,3-tetrafluoropropyl) carbonate in up to 60% yield. The degree of transesterification decreased in the series (i-PrO)(4)Ti > (EtO)(4)Ti > (BuO)(4)Ti and did not exceed 68%. The selectivity for alkyl 2,2,3,3-tetrafluoropropyl carbonates and bis(2,2,3,3-tetrafluoropropyl) carbonate was found to change depending on the composition of mixed titanium(IV) alkoxide formed in situ.
• Orlov, S. I.; Chimishkyan, A. L.; Elinevskii, A. V., Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, # 3, p. 417 - 420
  作者：Orlov, S. I.、Chimishkyan, A. L.、Elinevskii, A. V.、Grabarnik, M. S.

  DOI：——

  日期：——