sodium pentadecylate

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: sodium pentadecylate
• 英文别名: Sodium;pentadecan-1-olate
• 化学式: C₁₅H₃₁O*Na
• 分子量: 250.4
• InChiKey: VLSKJEJWKHBYCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.44
• 重原子数：
  17
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  sodium monochloroacetic acid 、 sodium pentadecylate 以 乙二醇二甲醚 为溶剂， 生成 2-(pentadecyloxy)acetic acid
  参考文献：
  名称：

  Mayer,B.; Asselineau,J., Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1966, vol. 262, p. 668 - 671

  摘要：

  DOI：

文献信息

• Production process of microspheres
  申请人：Eisai Co., Ltd.

  公开号：EP0461630A2

  公开（公告）日：1991-12-18

  Upon formation of a drug into microspheres by O/W solvent evaporation, a mixed solvent of at least one water-insoluble solvent and at least one water-miscible solvent is used as a solvent of an oil phase. A fatty acid or a salt thereof may be added to the mixed solvent. The oil phase may contain at least one glycerin fatty acid ester and/or at least one propylene glycol fatty acid ester, other than the mixed solvent. The oil phase may also comprise the mixed solvent; a fatty acid or a salt thereof; and at least one glycerin fatty acid ester and/or at least one propylene glycol fatty acid ester. The resulting drug-containing microspheres contain the drug at a high concentration and slowly release from the initial stage after administration.

  通过 O/W 溶剂蒸发法将药物制成微球时，使用至少一种水不溶性溶剂和至少一种水可混 溶性溶剂的混合溶剂作为油相溶剂。混合溶剂中可添加脂肪酸或其盐。除混合溶剂外，油相还可包含至少一种甘油脂肪酸酯和/或至少一种丙二醇脂肪酸酯。油相还可以包含混合溶剂、脂肪酸或其盐、至少一种甘油脂肪酸酯和/或至少一种丙二醇脂肪酸酯。由此产生的含药微球含有高浓度的药物，并在用药后的初始阶段缓慢释放。
• POLYCARBONATE RESIN COMPOSITION
  申请人：Teijin Limited

  公开号：EP3135727A1

  公开（公告）日：2017-03-01

  A polycarbonate resin composition comprising a polycarbonate resin and 0.001 to 1 parts by weight of an N-R type (R represents an alkyl group) hindered amine-based optical stabilizer per 100 parts by weight of the polycarbonate resin, wherein the polycarbonate resin comprises 40 mol% or more of a recurring unit (A) represented by the following formula and satisfies the following formulas (i) to (v), and the resin composition has excellent heat resistance, a low water absorption coefficient and high transparency, and suppresses deterioration during long-term use: (i) a metal compound comprising a negative ion represented by the following formula (B) and a positive ion constituted by a metal is used as a polymerization catalyst in an amount of 1 × 10-9 to 1 × 10-5 molar equivalent relative to the total diol compounds used for polymerization; (ii) the specific viscosity measured with a methylene chloride solution at 20°C is 0.23 to 0.60; (iii) the glass transition temperature is 100°C to 160°C; (iv) the saturated water absorption coefficient is 2.5% or less; and (v) the relationship between the glass transition temperature (Tg°C) and the saturated water absorption coefficient (Wa%) satisfies the following formula (I): 2.5≤Tw value=Tg×0.04−Wa wherein R1 is an alkylene group, a cycloalkylene group, or an arylalkylene group which has 1 to 22 carbon atoms and may be linear or branched.

  一种聚碳酸酯树脂组合物，包括聚碳酸酯树脂和每 100 份聚碳酸酯树脂重量含 0.001 至 1 份 N-R 型(R 代表烷基)受阻胺基光学稳定剂，其中聚碳酸酯树脂包含 40 摩尔％或更多由下式表示的循环单元(A)，并满足以下公式(i)至(v)，且该树脂组合物具有优异的耐热性、低吸水系数和高透明度，并在长期使用过程中抑制劣化： (i) 使用由下式（B）表示的负离子和金属构成的正离子组成的金属化合物作为聚合催化剂，其用量相对于用于聚合的二元醇化合物总量为 1 × 10-9 至 1 × 10-5 摩尔当量； (ii) 在 20°C 時以二氯甲烷溶液測得的比黏度為 0.23 至 0.60； (iii) 玻璃化转变温度为 100°C 至 160°C (iv) 饱和吸水系数为 2.5%或更低；以及 (v) 玻璃化转变温度(Tg°C)与饱和吸水系数(Wa%)之间的关系满足下式(I)：2.5≤Tw 值=Tg×0.04-Wa 其中，R1 是烷基、环烷基或芳基烷基，具有 1 至 22 个碳原子，可以是直链或支链。
• BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND METHOD FOR MEASURING BIOLOGICAL SIGNAL
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP3881766A1

  公开（公告）日：2021-09-22

  A bio-electrode includes an electro-conductive base material and a living body contact layer. The living body contact layer includes a water-free resin layer and a permeation layer on a surface side of the resin layer where a living body comes into contact. The permeation layer is permeated with water and a watersoluble salt selected from the group consisting of sodium salts, potassium salts, calcium salts, magnesium salts, and betaines. This aims to provide: a dry-type bio-electrode that enables quick signal collection after attachment to skin, the bio-electrode being excellent in electric conductivity and biocompatibility, light-weight, and manufacturable at low cost, and capable of preventing significant reduction in the electric conductivity even when wetted with water or dried; a method for manufacturing the bio-electrode; and a method for measuring a biological signal.

  生物电极包括导电基底材料和活体接触层。活体接触层包括无水树脂层和位于树脂层与活体接触表面一侧的渗透层。渗透层渗透有水和从钠盐、钾盐、钙盐、镁盐和甜菜碱组成的组中选出的水溶性盐。本发明旨在提供：一种干式生物电极，可在附着于皮肤后快速采集信号，该生物电极具有良好的导电性和生物相容性，重量轻，可低成本制造，即使被水浸湿或干燥，也能防止导电性显著降低；一种制造该生物电极的方法；以及一种测量生物信号的方法。
• BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, POLYMER COMPOUND, AND COMPOSITE
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP3984456A1

  公开（公告）日：2022-04-20

  A bio-electrode composition contains (A) a composite of an ionic polymer material and particles. The component (A) contains the particles bonding to the polymer containing a repeating unit having a structure selected from the group consisting of salts of ammonium, lithium, sodium, potassium, and silver formed with any of fluorosulfonic acid, fluorosulfonimide, and N-carbonyl-fluorosulfonamide. Thus, the present invention provides: a bio-electrode composition capable of forming a living body contact layer for a bio-electrode which is excellent in electric conductivity and biocompatibility, light-weight, and manufacturable at low cost, and which prevents significant reduction in the electric conductivity even when wetted with water or dried; a bio-electrode including a living body contact layer formed of the bio-electrode composition; and a method for manufacturing the bio-electrode.

  一种生物电极组合物包含（A）离子聚合物材料和颗粒的复合材料。组分（A）包含与聚合物粘合的颗粒，聚合物含有重复单元，该重复单元的结构选自由铵盐、锂盐、钠盐、钾盐和银盐组成的组，这些盐与氟磺酸、氟磺酰亚胺和 N-羰基-氟磺酰胺中的任意一种形成。因此，本发明提供了：一种能够为生物电极形成活体接触层的生物电极组合物，其导电性和生物相容性极佳，重量轻，可低成本制造，即使被水浸湿或干燥，也不会显著降低导电性；一种生物电极，包括由该生物电极组合物形成的活体接触层；以及一种制造该生物电极的方法。
• BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND SILICON MATERIAL PARTICLE
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP3968343A2

  公开（公告）日：2022-03-16

  A bio-electrode composition contains particles having surfaces with an N-carbonyl sulfonamide salt shown by the following general formula (1). R1 represents a linear, branched, or cyclic alkylene group having 1 to 20 carbon atoms and optionally having an aromatic group, ether group, or ester group, or an arylene group having 6 to 10 carbon atoms. Rf represents a linear, branched, or cyclic alkyl group having 1 to 4 carbon atoms, or an aryl group having 6 to 10 carbon atoms, and optionally has a fluorine atom. M+ represents an ion selected from the group consisting of lithium, sodium, potassium, and silver ions. This invention provides a bio-electrode composition capable of forming a living body contact layer for a bio-electrode which is excellent in electric conductivity and biocompatibility, light-weight, and manufacturable at low cost, and prevents significant reduction in electric conductivity even when wetted with water or dried.

  一种生物电极组合物含有表面具有如下通式（1）所示 N-羰基磺酰胺盐的颗粒。R1 代表具有 1 至 20 个碳原子的直链、支链或环状亚烷基，可选择具有芳香基、醚基或酯基，或具有 6 至 10 个碳原子的芳烯基。Rf 代表具有 1 至 4 个碳原子的直链、支链或环状烷基，或具有 6 至 10 个碳原子的芳基，并可选择具有一个氟原子。M+ 代表选自锂、钠、钾和银离子的离子。本发明提供了一种生物电极组合物，该组合物能够形成生物电极的活体接触层，具有优异的导电性和生物相容性，重量轻，可低成本制造，即使被水浸湿或干燥也不会显著降低导电性。