2-(4-Aza-1-azoniabicyclo[2.2.2]octan-1-yl)-1-naphthalen-1-ylethanone

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(4-Aza-1-azoniabicyclo[2.2.2]octan-1-yl)-1-naphthalen-1-ylethanone
• 化学式: C18H21N2O+
• 分子量: 281.4
• InChiKey: KHFFUPLQVUWPJP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• SUBSTRATES, SYSTEMS, AND METHODS FOR NUCLEIC ACID ARRAY SYNTHESIS
  申请人：Vibrant Holdings, LLC

  公开号：EP3402897A1

  公开（公告）日：2018-11-21
• Substrates, Systems, and Methods for Array Synthesis and Biomolecular Analysis
  申请人：Vibrant Holdings, LLC

  公开号：US20160288080A1

  公开（公告）日：2016-10-06

  Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N->C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.
• [EN] SUBSTRATES, SYSTEMS, AND METHODS FOR ARRAY SYNTHESIS AND BIOMOLECULAR ANALYSIS<br/>[FR] SUBSTRATS, SYSTÈMES ET PROCÉDÉS POUR LA SYNTHÈSE DE RÉSEAU ET L'ANALYSE BIOMOLÉCULAIRE
  申请人：VIBRANT HOLDINGS LLC

  公开号：WO2014078606A2

  公开（公告）日：2014-05-22

  Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N->C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.
• [EN] SUBSTRATES, SYSTEMS, AND METHODS FOR NUCLEIC ACID ARRAY SYNTHESIS<br/>[FR] SUBSTRATS, SYSTÈMES ET PROCÉDÉS POUR LA SYNTHÈSE DE MATRICES D'ACIDE NUCLÉIQUE
  申请人：VIBRANT HOLDINGS LLC

  公开号：WO2017117292A1

  公开（公告）日：2017-07-06

  Disclosed herein are formulations, substrates, and arrays for the synthesis of PNA chains and PNA-DNA chimera on microarrays. In some embodiments, the formulations include a photo-protective compound that shields any PNA monomers, PNA polymers, or PNA-DNA chimera already attached to a microarray from radiation exposure during the synthesis of the PNA or PNA-DNA chains. In some embodiments, substrates and arrays comprise a porous or a planar layer for synthesis and attachment of PNA or DNA monomers, or PNA or PNA-DNA polymers. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of PNA monomers or PNA polymers to a microarray substrate.