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分散黄 3 | 2832-40-8

中文名称
分散黄 3
中文别名
分散黄3;C.I.分散黄3;N-[4-[(2-羟基-5-甲基苯基)偶氮]苯基]乙酰胺;分散黄E-G;分散黄SE-G
英文名称
disperse yellow 3
英文别名
N-[4-[(2-hydroxy-5-methylphenyl)diazenyl]phenyl]acetamide
分散黄 3化学式
CAS
2832-40-8
化学式
C15H15N3O2
mdl
——
分子量
269.303
InChiKey
PXOZAFXVEWKXED-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

物化性质

  • 熔点:
    268-270 °C(lit.)
  • 沸点:
    412.44°C (rough estimate)
  • 密度:
    1.1385 (rough estimate)
  • 溶解度:
    氯仿(极少量)、DMSO(少量,超声处理)、甲醇(少量,超声处理)
  • 物理描述:
    C.i. disperse yellow 3 is a brownish-yellow powder. (NTP, 1992)
  • 蒸汽压力:
    5.00e-11 mmHg

计算性质

  • 辛醇/水分配系数(LogP):
    2.9
  • 重原子数:
    20
  • 可旋转键数:
    3
  • 环数:
    2.0
  • sp3杂化的碳原子比例:
    0.13
  • 拓扑面积:
    74
  • 氢给体数:
    2
  • 氢受体数:
    4

ADMET

毒理性
  • 致癌性证据
评估:对分散橙3在实验动物中的致癌性有有限证据。没有来自人类关于分散橙3致癌性的研究数据。总体评估:分散橙3的致癌性对人不可分类(第3组)。
Evaluation: There is limited evidence for the carcinogenicity of Disperse Yellow 3 in experimental animals. No data were available from studies in humans on the carcinogenicity of Disperse Yellow 3. Overall evaluation: Disperse Yellow 3 is not classifiable as to its carcinogenicity to humans (Group 3).
来源:Hazardous Substances Data Bank (HSDB)
毒理性
  • 致癌物分类
国际癌症研究机构致癌物:分散黄3
IARC Carcinogenic Agent:Disperse Yellow 3
来源:International Agency for Research on Cancer (IARC)
毒理性
  • 致癌物分类
国际癌症研究机构(IARC)致癌物分类:第3组:对其对人类的致癌性无法分类
IARC Carcinogenic Classes:Group 3: Not classifiable as to its carcinogenicity to humans
来源:International Agency for Research on Cancer (IARC)
毒理性
  • 致癌物分类
国际癌症研究机构专论集:第48卷:(1990年)一些阻燃剂和纺织化学品以及在纺织制造工业中的暴露
IARC Monographs:Volume 48: (1990) Some Flame Retardants and Textile Chemicals, and Exposures in the Textile Manufacturing Industry
来源:International Agency for Research on Cancer (IARC)
毒理性
  • 副作用
皮肤致敏剂 - 一种可以诱导皮肤产生过敏反应的制剂。
Skin Sensitizer - An agent that can induce an allergic reaction in the skin.
来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

安全信息

  • 危险品标志:
    Xn
  • 安全说明:
    S22,S36/37,S46
  • 危险类别码:
    R40
  • WGK Germany:
    2
  • 海关编码:
    2927000090
  • RTECS号:
    AC3662000

SDS

SDS:e792d11fc54f0bda6ff457373255ffc9
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SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifiers
Product name : Disperse Yellow 3
Index-No. : 611-055-00-0
REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not
require a registration or the registration is envisaged for a later
registration deadline.
CAS-No. : 2832-40-8


SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Carcinogenicity (Category 2), H351
Skin sensitisation (Category 1), H317
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
R40
R43
For the full text of the R-phrases mentioned in this Section, see Section 16.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal word Warning
Hazard statement(s)
May cause an allergic skin reaction.
Suspected of causing cancer.
Precautionary statement(s)
Wear protective gloves.
Supplemental Hazard none
Statements
Other hazards - none

SECTION 3: Composition/information on ingredients
Substances
Chemical characterization : Natural product
Synonyms : N-[4-(2-Hydroxy-5-methylphenylazo)phenyl]acetamide
4-(2-Hydroxy-5-methylphenylazo)acetanilide
Formula : C15H15N3O2
Molecular Weight : 269,3 g/mol
CAS-No. : 2832-40-8
EC-No. : 220-600-8
Index-No. : 611-055-00-0
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
4-(2-Hydroxy-5-methylphenylazo)acetanilide
CAS-No. 2832-40-8 Skin Sens. 1; Carc. 2; H317, <= 100 %
EC-No. 220-600-8
Index-No. 611-055-00-0
Hazardous ingredients according to Directive 1999/45/EC
Component Classification Concentration
4-(2-Hydroxy-5-methylphenylazo)acetanilide
CAS-No. 2832-40-8 Xn, Carc.Cat.3, R40 - R43 <= 100 %
EC-No. 220-600-8
Index-No. 611-055-00-0
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
no data available

SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx)
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Specific end use(s)
A part from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is advisory only and must
be evaluated by an industrial hygienist and safety officer familiar with the specific situation of
anticipated use by our customers. It should not be construed as offering an approval for any
specific use scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) Appearance Form: powder
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing Melting point/range: 268 - 270 °C - lit.
point
f) Initial boiling point and no data available
boiling range
g) Flash point no data available
h) Evapouration rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density no data available
n) Water solubility no data available
o) Partition coefficient: n- log Pow: 3,6
octanol/water
p) Auto-ignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available

SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Oxidizing agents
Hazardous decomposition products
Other decomposition products - no data available
In the event of fire: see section 5

SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitisation
Germ cell mutagenicity
Hamster
ovary
Sister chromatid exchange
mouse
DNA damage
Carcinogenicity
Carcinogenicity - rat - Oral
Tumorigenic:Carcinogenic by RTECS criteria. Liver:Tumors. Leukaemia
Carcinogenicity - mouse - Oral
Tumorigenic:Carcinogenic by RTECS criteria. Lungs, Thorax, or Respiration:Tumors. Liver:Tumors.
Carcinogenicity - mouse - Oral
Tumorigenic:Equivocal tumorigenic agent by RTECS criteria. Lungs, Thorax, or Respiration:Tumors.
Lungs, Thorax, or Respiration:Bronchiogenic carcinoma.
This product is or contains a component that has been reported to be possibly carcinogenic based on its
IARC, ACGIH, NTP, or EPA classification.
Limited evidence of carcinogenicity in animal studies
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Additional Information
RTECS: AC3662000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.

SECTION 12: Ecological information
Toxicity
Toxicity to fish LC50 - Pimephales promelas (fathead minnow) - > 180 mg/l - 96 h
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
no data available

SECTION 13: Disposal considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

SECTION 14: Transport information
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available

SECTION 15: Regulatory information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
Chemical Safety Assessment


SECTION 16 - ADDITIONAL INFORMATION
N/A


制备方法与用途

简介

分散黄3是重要的化工原料,可通过合成或从煤焦油中提取。不过,在这两种方法中都需要经过一系列的分离与提纯过程,导致原材料不能完全利用,同时也增加了环保压力。

在染料化工领域,一直以来都使用单一酚及其衍生物来制备各种黄色染料,尤其是分散黄3。

制备

对氨基乙酰苯胺进行重氮化后,再与其偶合,可以得到一系列黄色染料。当与对甲基苯酚发生偶合时,则可制得C.I.分散黄3。

用途

主要用于涤纶及其混纺织物的染色。

类别

有毒物品

毒性分级

低毒

急性毒性
  • 腹腔注射 - 大鼠 LD50: 8190 毫克/公斤
  • 腹腔注射 - 小鼠 LD50: 8080 毫克/公斤
爆炸物危险特性

过敏效应

可燃性危险特性

可燃;加热分解会释放有毒氮氧化物烟雾

储运特性

应存放在通风、低温、干燥的库房内。

灭火剂

干粉、泡沫、砂土和水。

反应信息

  • 作为反应物:
    描述:
    分散黄 3 在 sodium carbonate 作用下, 以 丙酮 为溶剂, 反应 16.0h, 生成
    参考文献:
    名称:
    一种含偶氮结构阳离子活性染料及其制备方法
    摘要:
    本发明提供一种如图(1)所示的含偶氮结构阳离子活性染料及其制备方法。首先利用仲胺化合物与甲氧基聚乙二醇缩水甘油醚反应,制备出2‑羟基‑3‑甲基聚醚基取代丙基叔胺化合物,然后利用卤代均三嗪将其与含有羟基或氨基的偶氮分散染料发色体进行连接,最后再将产物中的叔胺进行季铵化,制备出含偶氮结构阳离子活性染料。此阳离子活性染料色谱齐全,水溶性可调节,对纤维素纤维直接性高,可以进行无盐染色,其制备方法简单,成本低。
    公开号:
    CN107353671A
  • 作为产物:
    描述:
    对甲酚4′-氨基乙酰苯胺盐酸 、 sodium nitrite 作用下, 生成 分散黄 3
    参考文献:
    名称:
    Masoud, Mamdouh S.; Osman, M. M.; Salem, T. M., Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1981, vol. 20, # 6, p. 584 - 587
    摘要:
    DOI:
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文献信息

  • POLYMERIZABLE YELLOW DYE FOR MANUFACTURING OPHTHALMIC LENS
    申请人:BenQ Materials Corporation
    公开号:US20140378672A1
    公开(公告)日:2014-12-25
    A polymerizable yellow dye which is used to block or lower the intensity of blue light transmitted through ophthalmic lenses and is represented by the following formula (I): wherein R 1 is hydrogen or —NHCOCH 3 ; R 2 is hydrogen or C 1 -C 3 alkyl groups; R 3 and R 4 are independently hydrogen or —OCO—R 5 , wherein R 5 is isopropenyl group or a substituted isopropenyl group represented as —R 6 —(R 7 O) n —COC(CH 3 )CH 2 , R 6 is NH or R 7 is C 1 -C 5 alkylene groups and n is an integer of 1-40.
    一种可聚合的黄色染料,用于阻挡或降低透过眼镜的蓝光强度,其化学式如下(I):其中R1是氢或—NHCOCH3;R2是氢或C1-C3烷基基团;R3和R4独立地是氢或—OCO—R5,其中R5是异丙烯基或表示为—R6—(R7O)n—COC(CH3)CH2的取代异丙烯基,R6是NH或R7是C1-C5烷基基团,n为1-40的整数。
  • 一种含偶氮结构阳离子活性染料及其制备方法
    申请人:南京工业大学
    公开号:CN107353671A
    公开(公告)日:2017-11-17
    本发明提供一种如图(1)所示的含偶氮结构阳离子活性染料及其制备方法。首先利用仲胺化合物与甲氧基聚乙二醇缩水甘油醚反应,制备出2‑羟基‑3‑甲基聚醚基取代丙基叔胺化合物,然后利用卤代均三嗪将其与含有羟基或氨基的偶氮分散染料发色体进行连接,最后再将产物中的叔胺进行季铵化,制备出含偶氮结构阳离子活性染料。此阳离子活性染料色谱齐全,水溶性可调节,对纤维素纤维直接性高,可以进行无盐染色,其制备方法简单,成本低。
  • Masoud, Mamdouh S.; Osman, M. M.; Salem, T. M., Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1981, vol. 20, # 6, p. 584 - 587
    作者:Masoud, Mamdouh S.、Osman, M. M.、Salem, T. M.、Khalil, E. A.
    DOI:——
    日期:——
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表征谱图

  • 氢谱
    1HNMR
  • 质谱
    MS
  • 碳谱
    13CNMR
  • 红外
    IR
  • 拉曼
    Raman
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mass
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ir
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  • 峰位数据
  • 峰位匹配
  • 表征信息
Shift(ppm)
Intensity
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Assign
Shift(ppm)
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测试频率
样品用量
溶剂
溶剂用量
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同类化合物

黑洞猝灭剂-2,BHQ-2ACID 麦角甾烷-6-酮,2,3,22,23-四羟基-,(2a,3a,5a,22S,23S,24S)- 颜料橙61 阿利新黄GXS 阳离子红X-GTL 阳离子红5BL 阳离子橙RN 阳离子橙GLH 间甲基红 镨(3+)丙烯酰酸酯 镍酸酯(1-),[3-羟基-4-[(4-甲基-3-硫代苯基)偶氮]-2-萘羧酸根(3-)]-,氢 钴,[二[m-[[1,2-二苯基-1,2-乙二酮1,2-二(肟酸根-kO)](2-)]]四氟二硼酸根(2-)-kN1,kN1',k2,kN2']-,(SP-4-1)- 钠5-氯-2-羟基-3-[(2-羟基-4-{[(4-甲基苯基)磺酰基]氧基}苯基)偶氮]苯磺酸酯 钠5-[[3-[[5-[[4-[[[4-[(4,5-二氢-3-甲基-5-氧代-1H-吡唑-4-基)偶氮]苯基]氨基]羰基]苯基]偶氮]-2,4-二羟基苯基]偶氮]-4-羟基苯基]偶氮]水杨酸盐 钠4-[(4-氨基苯基)偶氮]苯甲酸酯 钠4-[(4-{[4-(二乙基氨基)苯基]偶氮}苯基)偶氮]苯磺酸酯 钠4-({3-甲氧基-4-[(4-甲氧基苯基)偶氮]苯基}偶氮)苯磺酸酯 钠3-({5-甲氧基-4-[(4-甲氧基苯基)偶氮]-2-甲基苯基}偶氮)苯磺酸酯 重氮基烯,苯基[4-(三氟甲基)苯基]- 重氮基烯,[4-[(2-乙基己基)氧代]-2,5-二甲基苯基](4-硝基苯基)- 重氮基烯,(2-氯苯基)苯基- 酸性金黄G 酸性棕S-BL 酸性媒介棕6 酸性媒介棕48 酸性媒介棕4 酸性媒介棕24 邻氨基偶氮甲苯 达布氨乙基甲硫基磺酸盐 赛甲氧星 茴香酸盐己基 苯重氮化,2-甲氧基-5-甲基-4-[(4-甲基-2-硝基苯基)偶氮]-,氯化 苯酰胺,4-[4-(2,3-二氢-1,4-苯并二噁英-6-基)-5-(2-吡啶基)-1H-咪唑-2-基]- 苯胺棕 苯胺,4-[(4-氯-2-硝基苯基)偶氮]- 苯甲酸,2-[3-[4-(苯偶氮基)苯基]-1-三氮烯基基]- 苯基-(4-苯基偶氮苯基)二氮烯 苯基-(4-哌啶-1-基苯基)二氮烯 苯基-(4-吡咯烷-1-基苯基)二氮烯 苯乙酸,-α-,4-二甲基-,(-alpha-S)-(9CI) 苏丹红 苏丹橙G 苏丹Ⅳ 膦酸,[(2-羟基苯基)[[4-(苯偶氮基)苯基]氨基]甲基]-,二乙基酯 脂绯红 耐晒深蓝R盐 耐晒枣红GBC 羰基[苯基(丙烷-2-基)氨基]乙酸 美沙拉嗪杂质06 美沙拉嗪杂质05

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