sodium methyl(2-methylperhydro-1,3-diazin-2-yl)phosphinate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: sodium methyl(2-methylperhydro-1,3-diazin-2-yl)phosphinate
• 英文别名: sodium;methyl-(2-methyl-1,3-diazinan-2-yl)phosphinate
• 化学式: C₆H₁₄N₂O₂P*Na
• 分子量: 200.153
• InChiKey: QXDBQWARLUHPCN-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.48
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  64.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  sodium acetylmethylphosphinate 、 1,3-丙二胺 以 乙醇 为溶剂， 以95%的产率得到sodium methyl(2-methylperhydro-1,3-diazin-2-yl)phosphinate
  参考文献：
  名称：

  Compounds and compositions

  摘要：

  描述了包含化学式I中一个或多个化合物的杀虫组合物，其中Ra是一个基团R.sup.2或--OR.sup.2，E是氧或硫，Rm是--O.sup..crclbar. M.sup..sym.或--NRyRz，M.sup..sym.是一当量的农业可接受阳离子，R.sup.1和R.sup.2，可能相同也可能不同，分别代表氢、烷基、烯基、炔基或芳基；所述烷基、烯基、炔基或芳基可以选择性地被一个或多个卤素、烷氧基、硝基、烷基、--CF.sub.3、腈基或羧酸或其盐、酯或酰胺取代，Ry和Rz，可能相同也可能不同，分别代表氢或烷基，或其农业可接受的衍生物。还描述了制备和使用化学式I中化合物的方法。

  公开号：

  US04339443A1

文献信息

• DENTAL ADHESIVE
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US20170196778A1

  公开（公告）日：2017-07-13

  The present invention provides a dental adhesive exhibiting excellent initial bond strength and bond durability to both enamel and dentin. The present invention relates to a dental adhesive containing: an asymmetric acrylamide-methacrylic acid ester compound (a); an acid group-containing (meth)acrylic polymerizable monomer (b); and a water-soluble polymerizable monomer (c). The asymmetric acrylamide-methacrylic acid ester compound (a) is represented by the following general formula (1): where X is an optionally substituted, linear or branched C 1 to C 6 aliphatic group or an optionally substituted aromatic group, the aliphatic group is optionally interrupted by at least one linking group selected from the group consisting of —O—, —S—, —CO—, —CO—O—, —O—CO—, —NR 1 —, —CO—NR 1 —, —NR 1 —CO—, —CO—O—NR 1 —, —O—CO—NR 1 —, and —NR 1 —CO—NR 1 —, and R 1 is a hydrogen atom or an optionally substituted, linear or branched C 1 to C 6 aliphatic group.

  本发明提供了一种牙科粘接剂，具有优异的初始粘接强度和对牙釉质和牙本质的粘接耐久性。本发明涉及一种含有以下成分的牙科粘接剂：不对称丙烯酰胺-甲基丙烯酸酯化合物（a）；含酸基的（甲基）丙烯酸聚合单体（b）；以及水溶性聚合单体（c）。不对称丙烯酰胺-甲基丙烯酸酯化合物（a）由下述一般式（1）表示：其中X是可选择取代的线性或支链状的C1到C6脂肪族基或可选择取代的芳香族基，所述脂肪族基可被来自由—O—、—S—、—CO—、—CO—O—、—O—CO—、—NR1—、—CO—NR1—、—NR1—CO—、—CO—O—NR1—、—O—CO—NR1—和—NR1—CO—NR1—组成的至少一个连接基中断，R1为氢原子或可选择取代的线性或支链状的C1到C6脂肪族基。
• Pesticidally active salts and compositions containing them and processes for their manufacture and use
  申请人：FBC LIMITED

  公开号：EP0009348A2

  公开（公告）日：1980-04-02

  There are described pesticidal compositions comprising one or more compounds of the formula 1, in which Ra is a group R2 or -OR2, E is oxygen or sulphur, Rm is-O⊖M⊕ or -NRyRz, M⊕ is one equivalent of an agriculturally acceptable cation, R1 and R2, which may be the same or different, each represent hydrogen, alkyl, alkenyl, alkynyl or aryl; the alkyl, alkenyl, alkynyl or aryl optionally being substituted by one or more halogen, alkoxy, nitro, alkyl, -CH3, nitrile, or carboxylic acid or a salt, ester, or amide thereof, and Ry and Rz, which may be the same or different, each represent hydrogen or alkyl, or an agriculturally acceptable derivative thereof. There are also described methods for making and using compounds of formula I.

  所述杀虫剂组合物包含一种或多种式 1、 其中 Ra 是基团 R2 或 -OR2、 E 是氧或硫、 Rm 是-O⊖M⊕或-NRyRz、 M⊕ 是一个等价的农业上可接受的阳离子、 R1 和 R2，可以相同或不同，各自代表氢、烷基、烯基、炔基或芳基；烷基、烯基、炔基或芳基可选择被一个或多个卤素、烷氧基、硝基、烷基、-CH3、腈或羧酸或其盐、酯或酰胺取代，以及 Ry和Rz可以相同或不同，各自代表氢或烷基、 或其农业上可接受的衍生物。 还描述了制造和使用式 I 化合物的方法。
• POLYMERIZABLE MONOMER-CONTAINING COMPOSITION
  申请人：Kuraray Medical Inc.

  公开号：EP2112177A1

  公开（公告）日：2009-10-28

  The present invention provides a composition suitable for a dental composition. The present invention is a composition containing: a polymerizable monomer (A) having an unconjugated carbon chain with at least four carbon atoms bonded continuously, at least two polymerizable groups, and at least two hydroxyl groups; and a water (B). The composition contains 6 to 2000 parts by weight of the water (B) with respect to 100 parts by weight of the whole amount of polymerizable monomer components. When suitable components are added to this composition, the resultant composition can be used suitably for dental materials such as a primer, bonding material, composite resin, and cement.

  本发明提供了一种适用于牙科组合物的组合物。本发明的组合物含有：可聚合单体（A），其具有至少四个碳原子连续键合的非共轭碳链、至少两个可聚合基团和至少两个羟基；以及水（B）。相对于 100 重量份的可聚合单体成分总量，该组合物含有 6 至 2000 重量份的水（B）。在该组合物中加入适当的成分后，所得到的组合物可用于牙科材料，如底漆、粘合材料、复合树脂和水泥。
• POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL
  申请人：Kuraray Medical Inc.

  公开号：EP2108663A1

  公开（公告）日：2009-10-14

  The present invention provides a polymerizable composition that exhibits excellent adhesive properties to a tooth structure (particularly dentin) when applied as a dental material, and a polymerizable monomer that is used as a component of the polymerizable composition. The present invention is a polymerizable monomer (A) that is a compound having at least two polymerizable groups. The polymerizable monomer (A) has a retention time of 7 minutes to 30 minutes in a high-performance liquid chromatography (HPLC) measurement conducted under a condition in which a column with an inner diameter of 3.9 mm and a length of 300 mm, packed with a C18 packing material having been crushed to have an average particle size of 10 µm and a pore size of 125 angstroms, is used, an eluent is a mixed solvent of methanol and water contained at a ratio of 3:7, a flow rate is 1.0 mL/minute, a measurement temperature is 50°C, a sample injection volume is 10 µL, and a dead volume from a sample inlet to a detection point excluding the column is 87 µL. The present invention also is a composition containing the polymerizable monomer (A).

  本发明提供了一种可聚合组合物，该组合物在作为牙科材料应用时对牙齿结构（特别是牙本质）具有优异的粘合性能，本发明还提供了一种可聚合单体，该单体用作可聚合组合物的组分。本发明的可聚合单体（A）是一种具有至少两个可聚合基团的化合物。可聚合单体（A）在高效液相色谱（HPLC）测量中的保留时间为 7 分钟至 30 分钟，测量条件为色谱柱内径为 3.9毫米，长度为300毫米，填料为平均粒径为10微米，孔径为125埃的C18填料，洗脱液为甲醇和水的混合溶剂，比例为3:7，流速为1.0毫升/分钟，测量温度为50℃，进样量为10微升，从进样口到不包括色谱柱的检测点的死体积为87微升。本发明也是一种含有可聚合单体（A）的组合物。
• COMPOSITION AND DENTAL MATERIAL
  申请人：Kuraray Medical Inc.

  公开号：EP2108664A1

  公开（公告）日：2009-10-14

  The present invention provides a composition that exhibits excellent adhesive properties to tooth structure (particularly dentin) when applied as a dental material. The present invention is a composition containing a polymerizable monomer (A) having an unconjugated carbon chain with at least four carbon atoms bonded continuously, at least two polymerizable groups, and at least two hydroxyl groups, and a bisacylphosphine oxide (B) represented by the following formula (1): where the respective symbols are as defined in the specification.

  本发明提供了一种组合物，该组合物作为牙科材料使用时，对牙齿结构（特别是牙本质）具有优异的粘合性能。本发明是一种含有可聚合单体（A）和双酰基氧化膦（B）的组合物，可聚合单体（A）具有连续键合至少四个碳原子的非共轭碳链、至少两个可聚合基团和至少两个羟基，双酰基氧化膦（B）由下式（1）表示： 其中各符号如说明书中所定义。