3,3-Diethyl-1,4-dioxane-2,5-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二恶烷
• 英文名称: 3,3-Diethyl-1,4-dioxane-2,5-dione
• 化学式: C₈H₁₂O₄
• 分子量: 172.18
• InChiKey: QMDUQRDPJXKZAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Antimicrobial polymer compositions and the use thereof
  申请人：Emeta Modesto

  公开号：US20060263330A1

  公开（公告）日：2006-11-23

  An antimicrobial composition comprising: a complex of an anionic polyester with an antimicrobial metal wherein the anionic polyester has at least one carboxylic acid group. A medical device having an antimicrobial composition comprising: a complex of an anionic polyester with an antimicrobial metal wherein the anionic polyester has at least one carboxylic acid group.

  一种抗菌组合物，包括：一种阴离子聚酯与一种含有至少一个羧酸基团的抗菌金属的复合物。包括抗菌组合物的医疗器械，其中该抗菌组合物包括：一种阴离子聚酯与一种含有至少一个羧酸基团的抗菌金属的复合物。
• ANTIMICROBIAL POLYMER COMPOSITIONS AND THE USE THEREOF
  申请人：ERNETA Modesto

  公开号：US20090092648A1

  公开（公告）日：2009-04-09

  An antimicrobial composition. The antimicrobial composition includes a complex of an anionic polyester with a monomeric amidoamine a complex of an anionic polyester with a monomeric amidoamine or an organic cation, wherein the monomeric amidoamine comprises: (R 1,2 )N—R 3 —NH—CO—R 4 wherein: R 1 ═H, Alkyl, Aryl, HO—(CH 2 CH 2 —O—) n —, MeO—(CH 2 CH 2 —O—) n —, HO—(CH 2 ) n —; R 2 ═H, Alkyl, Aryl, HO—(CH 2 CH 2 —O—) n —, MeO—(CH 2 CH 2 —O—) n —, HO—(CH 2 ) n —; R 3 =Alkyl, Aryl, —(CH 2 CH 2 —O—)—(CH 2 —) n ; R 4 =Alkyl, Aryl, —(CH 2 CH 2 —O—)—(CH 2 —) n —CH 3 , —O—CH 3 , —O—C 2 H 5 , —O—C 3 H 7 ; and n=1-30; and wherein the organic cation comprises: wherein: R 1 ═H, Alkyl, Aryl, HO—(CH 2 CH2-O—)n-, MeO—(CH2CH2-O—)n-, HO—(CH 2 )n-; R 2 ═H, Alkyl, Aryl, HO—(CH 2 CH2-O—)n-, MeO—(CH2CH2-O—)n, HO—(CH 2 )n-; R 3 ═H, Alkyl, Aryl, —(CH 2 CH 2 —O—)—(CH 2 —)n; R 4,5 ═H, Alkyl, Aryl, —(CH 2 CH 2 —O—)—(CH 2 -)n-CH 3 , —O—CH 3 , —O—C 2 H 5 , —O—C 3 H 7 ; and n=1-30; and the anionic polyester is selected from the group consisting of an anionic polyester having at least one carboxylic group, a sulfonic acid polymer, and a phosphoric acid polymer. A medical device having an antimicrobial composition that includes a complex of an anionic polyester with a monomeric amidoamine having at least one amide group and at least one amine group, wherein the amine group is either a primary amine, or a secondary amine, or a tertiary amine, or a quaternary amine, or a combination thereof and the anionic polyester has at least one carboxylic group is also provided.

  一种抗微生物组合物。该抗微生物组合物包括阴离子聚酯与单体酰胺胺的复合物，其中单体酰胺胺包括：(R1,2)N—R3—NH—CO—R4其中：R1═H，烷基，芳基，HO—( —O—)n—，MeO—( —O—)n—，HO—(CH2)n—；R2═H，烷基，芳基，HO—( —O—)n—，MeO—( —O—)n—，HO—( )n—；R3=烷基，芳基，—( —O—)—( —)n；R4=烷基，芳基，—( —O—)—( —)n—CH3，—O— ，—O—C2H5，—O—C3H7；n=1-30；有机阳离子包括：其中：R1═H，烷基，芳基，HO—( -O—)n-，MeO—( -O—)n-，HO—( )n-；R2═H，烷基，芳基，HO—( -O—)n-，MeO—( -O—)n，HO—( )n-；R3═H，烷基，芳基，—( —O—)—( —)n；R4,5═H，烷基，芳基，—( —O—)—( -)n- ，—O— ，—O— ，—O— ；n=1-30；阴离子聚酯选自包括至少一个羧基的阴离子聚酯、磺酸聚合物和磷酸聚合物的组。还提供了一种具有抗微生物组合物的医疗器械，该组合物包括阴离子聚酯与至少一个酰胺基团和至少一个胺基的单体酰胺胺的复合物，其中胺基是一次胺基、二次胺基、三次胺基、季胺基或其组合，且阴离子聚酯具有至少一个羧基。
• MRI-VISIBLE HYDROPHOBIC COPOLYMER
  申请人：Centre National de la Recherche Scientifique

  公开号：US20140302324A1

  公开（公告）日：2014-10-09

  The invention relates to a hydrophobic thermoplastic copolymer which is in particular of use for manufacturing and/or coating medical devices, in particular implantable medical devices, characterized in that it is obtained by copolymerization, and in that it comprises at least one first monomer unit and at least one second monomer unit onto which is grafted a paramagnetic-ion-chelating ligand which can complex with such a paramagnetic ion or a paramagnetic-ion-chelating ligand which is complexed with such a paramagnetic ion, wherein the second monomer unit is grafted in sufficient amount for the copolymer to be visible in magnetic resonance imaging when it is complexed with said paramagnetic ion. The invention also relates to a method for obtaining said hydrophobic thermoplastic copolymer.

  本发明涉及一种疏水性热塑性共聚物，特别适用于制造和/或涂层医疗器械，特别是可植入医疗器械。该共聚物通过共聚得到，并且包含至少一个第一单体单元和至少一个第二单体单元，该第二单体单元上嫁接有可以与该顺磁离子形成络合物的顺磁离子螯合配体，或者与该顺磁离子形成络合物的顺磁离子螯合配体，其中第二单体单元的嫁接量足够使共聚物在与所述顺磁离子形成络合物时在磁共振成像中可见。本发明还涉及一种获得该疏水性热塑性共聚物的方法。
• Segmented absorbable copolymer
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0460428A2

  公开（公告）日：1991-12-11

  A copolymer comprising a bioabsorbable, segmented molecular architecture has been invented. The copolymer has at least two different ester linkages. The segmented molecular architecture comprises a plurality of fast transesterifying linkages. The fast transesterifying linkages have a segment length distribution of greater than 1.3. The segmented molecular architecture also comprises a plurality of slow transesterifying linkages. The copolymer is useful as an article of manufacture, for example a molding resin, surgical element and controlled release device.

  我们发明了一种共聚物，它具有可生物吸收的分段式分子结构。该共聚物具有至少两种不同的酯连接。分段分子结构包括多个快速酯化链节。快速酯化链节的链节长度分布大于 1.3。分段分子结构还包括多个慢速酯化链节。这种共聚物可用作制造品，例如成型树脂、外科元件和控释装置。
• Copolymers of an aromatic anhydride and aliphatic ester
  申请人：ETHICON, INC.

  公开号：EP0636639A1

  公开（公告）日：1995-02-01

  A copolymer of an aromatic anhydride and an aliphatic ester suitable for use in surgical devices and a process for making said copolymer.

  一种适用于手术器械的芳香酸酐和脂肪族酯的共聚物，以及一种制造上述共聚物的工艺。