3-{3,5-dibromo-4-[(5-methylisoxazol-3-yl)methoxy]phenyl}propanoic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 3-{3,5-dibromo-4-[(5-methylisoxazol-3-yl)methoxy]phenyl}propanoic acid
• 英文别名: 3-[3,5-Dibromo-4-[(5-methyl-1,2-oxazol-3-yl)methoxy]phenyl]propanoic acid
• 化学式: C₁₄H₁₃Br₂NO₄
• 分子量: 419.07
• InChiKey: PZUKKWPNYCJJPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  72.6
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Novel Pharmaceutical Compositions
  申请人：Garg Neeraj

  公开号：US20080027096A1

  公开（公告）日：2008-01-31

  The invention provides compounds of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt, for use in the treatment or prophylaxis of condition mediated by an androgen receptor.

  该发明提供了公式(I)的化合物或其药学上可接受的酯、酰胺、溶剂或盐，包括这种酯或酰胺的盐和这种酯、酰胺或盐的溶剂，用于治疗或预防由雄激素受体介导的疾病。
• NOVEL PHARMACEUTICAL COMPOSITIONS
  申请人：KARO BIO AB

  公开号：EP1729756A2

  公开（公告）日：2006-12-13
• [EN] NOVEL PHARMACEUTICAL COMPOSITIONS<br/>[FR] NOUVELLES COMPOSITIONS PHARMACEUTIQUES
  申请人：KAROBIO AB

  公开号：WO2005094810A2

  公开（公告）日：2005-10-13

  The invention provides compounds of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt, for use in the treatment or prophylaxis of condition mediated by an androgen receptor.