3-amino-1,4-dioxonaphthalene-2-carboxylic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-amino-1,4-dioxonaphthalene-2-carboxylic acid
• 化学式: C₁₁H₇NO₄
• 分子量: 217.18
• InChiKey: GXDIXDKPIUJGOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  97.5
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• CARBON MEMBRANE HAVING BIOLOGICAL MOLECULE IMMOBILIZED THEREON
  申请人：Yoshida Youichi

  公开号：US20090192297A1

  公开（公告）日：2009-07-30

  Disclosed is a biological molecule-immobilized carbon membrane which comprises a porous carbon membrane and a biological molecule (e.g., an enzyme) immobilized on the carbon membrane, wherein the porous carbon membrane has three-dimensional cancellous pores through which fluid can permeate. The carbon membrane can have a large amount of a biological molecule (e.g., an enzyme) immobilized thereon and can also have a higher level of enzymatic activity or the like compared to a conventional one. Therefore, the carbon membrane is useful as an electrode for a bio-sensor or a bio-fuel cell.

  本发明涉及一种生物分子固定化的碳膜，包括多孔碳膜和生物分子（例如酶）固定在碳膜上，其中多孔碳膜具有三维海绵状孔隙，液体可以穿过其中。碳膜可以在其上固定大量的生物分子（例如酶），并且相比传统碳膜具有更高的酶活性等级。因此，碳膜可用作生物传感器或生物燃料电池的电极。
• FOOD MATERIALS USEFUL IN PREVENTING AND AMELIORATING METABOLIC BONE DISEASES AND PREVENTIVES/REMEDIES FOR METABOLIC BONE DISEASES COMPRISING THESE MATERIALS
  申请人：Meiji Dairies Corporation

  公开号：EP1230920A1

  公开（公告）日：2002-08-14

  This invention relates to drinks and foods having osteogenetic function, each of which comprises as an active ingredient an effective amount of a culture of a propionic acid bacterium and/or a lactic acid bacterium, said culture containing 2-amino-3-carboxy-1,4-naphthoquinone; and preventives and/or remedies for metabolic bone diseases, each of which comprises as an active ingredient a naphthoquinone compound selected from the group consisting of 2-amino-3-carboxy-1,4-naphthoquinone, 1,4-naphthoquinone, 2-hydroxy-1,4-naphthoquinone, 2,3-dichloro-1,4-naphthoquinone, 5-hydroxy-1,4-naphthoquinone, 8-hydroxy-1,4-naphthoquinone, 2-(α-hydroxy-δ-methylpentenyl)-5,8-dihydroxy-1,4-naphthoq uinone and salts thereof. These cultures and naphthoquinones promote bone metabolism and increase bone mass and bone strength.

  本发明涉及具有骨生成功能的饮料和食品，其中每种饮料和食品都包含有效量的丙酸细菌和/或乳酸细菌培养物作为活性成分，所述培养物含有2-氨基-3-羧基-1,4-萘醌；以及代谢性骨病的预防剂和/或治疗剂，其中每一种都包含一种萘醌化合物作为有效成 分，该化合物选自由 2-氨基-3-羧基-1,4-萘醌、1、4-萘醌、2-羟基-1,4-萘醌、2,3-二氯-1,4-萘醌、5-羟基-1,4-萘醌、8-羟基-1,4-萘醌、2-(α-羟基-δ-甲基戊烯基)-5,8-二羟基-1,4-萘醌及其盐类。这些培养物和萘醌能促进骨代谢，增加骨量和骨强度。
• PROCESS FOR PRODUCING 1,4-DIHYDROXY-2-NAPHTHOIC ACID
  申请人：Meiji Dairies Corporation

  公开号：EP1416052A1

  公开（公告）日：2004-05-06

  A composition containing 1,4-dihydroxy-2-naphthoic acid at a high concentration is obtained by intracellularly and extracellularly producing 1,4-dihydroxy-2-naphthoic acid using a bacterium belonging to the genus Propionibacterium and collecting it. This composition is efficacious in improving intestinal flora, alleviating abdominal ailments in association with the intake of milk, and preventing metabolic bone diseases.

  一种含有高浓度 1,4-二羟基-2-萘甲酸的组合物是通过使用一种属于丙酸杆菌属的细菌在细胞内和细胞外产生 1,4-二羟基-2-萘甲酸并将其收集而得到的。这种成分对改善肠道菌群、缓解与牛奶摄入有关的腹部疾病和预防代谢性骨病具有功效。
• IMMOBILIZATION SUPPORT, PROCESS FOR PRODUCING THE SAME, ELECTRODE, PROCESS FOR PRODUCING THE SAME, ELECTRODE REACTION UTILIZING APPARATUS AND PROCESS FOR PRODUCING THE SAME
  申请人：SONY CORPORATION

  公开号：EP1630227A1

  公开（公告）日：2006-03-01

  An immobilization carrier containing an electron acceptor compound is used in addition to glutaraldehyde and poly-L-lysine to immobilize an enzyme and an electron acceptor compound simultaneously to an electrode. For example, here are used diaphorase as the enzyme and 2-amino-3-carboxy-1, 4-naphthoquinone (ACNQ) as the electron acceptor compound.

  除了戊二醛和聚 L-赖氨酸之外，还使用了含有电子受体化合物的固定载体，将酶和电子受体化合物同时固定在电极上。例如，这里使用二磷酸酶作为酶，2-氨基-3-羧基-1，4-萘醌（ACNQ）作为电子受体化合物。
• FEEDING STUFF COMPOSITION COMPRISING PROLIFERATION PROMOTING AGENT FOR BIFIDUS BACTERIA AND USE OF THE SAME
  申请人：Meiji Dairies Corporation

  公开号：EP1867238A1

  公开（公告）日：2007-12-19

  The present invention relates to a feed composition comprising milk whey fermented by Propionibacterium and a method for forming and/or establishing a Bifidobacterium flora in an intestine of a newborn domestic animal, which comprises administering the feed composition to the newborn domestic animals.

  本发明涉及一种由丙酸杆菌发酵的牛奶乳清组成的饲料组合物，以及一种在新生家畜肠道中形成和/或建立双歧杆菌菌群的方法，该方法包括向新生家畜施用该饲料组合物。