2-Methylsulfonylethyl 2-(6-methoxynaphthalen-2-yl)propanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-Methylsulfonylethyl 2-(6-methoxynaphthalen-2-yl)propanoate
• 化学式: C₁₇H₂₀O₅S
• 分子量: 336.4
• InChiKey: JGBUBSOKFSVXKS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  78
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• COMPOSITIONS INCLUDING LEUKOTRIENE ANTAGONISTS AND NSAIDS AND METHODS OF USING THE SAME
  申请人：Fink Mitchell P.

  公开号：US20100221334A1

  公开（公告）日：2010-09-02

  Pharmaceutical compositions containing non-steroidal anti-inflammatory drugs (NSAIDs) and modified NSAIDs and leukotriene antagonists and methods for using such pharmaceutical compositions are provided herein. In a preffered embodiment naproxene 2-(methanesulfonyl)-ethyl ester is used in combination with Zileuton.
• METHOD OF TREATING ARTHRITIS, PAIN OR INFLAMMATION WITH NAPROXEN 2(METHANESULFONYL)ETHYL ESTER AND A PROTON PUMP INHIBITOR
  申请人：Fink Mitchell P.

  公开号：US20100221336A1

  公开（公告）日：2010-09-02

  Embodiments of the present invention provide methods of treating pain, arthritis and inflammation comprising administering naproxen 2(methanesulfonyl)ethyl ester and a proton pump inhibitor. Further embodiments provide pharmaceutical compositions comprising naproxen 2(methanesulfonyl)ethyl ester and a proton pump inhibitor.
• METHOD OF TREATING ARTHRITIS, PAIN OR INFLAMMATION WITH NAPROXEN 2(METHANESULFONYL)ETHYL ESTER AND AN H2 RECEPTOR ANTAGONIST
  申请人：Fink Mitchell P.

  公开号：US20100221337A1

  公开（公告）日：2010-09-02

  Embodiments of the present invention provide methods of treating pain, arthritis and inflammation comprising administering naproxen 2(methanesulfonyl)ethyl ester and an H2 receptor antagonist. Further embodiments provide pharmaceutical compositions comprising naproxen 2(methanesulfonyl)ethyl ester and an H2 receptor antagonist.
• USRE41151E1
  申请人：——

  公开号：USRE41151E1

  公开（公告）日：2010-02-23
• [EN] COMPOSITIONS INCLUDING LEUKOTRIENE ANTAGONISTS AND NSAIDS AND METHODS OF USING THE SAME<br/>[FR] COMPOSITIONS COMPRENANT DES ANTAGONISTES DES LEUCOTRIÈNES ET DES NSAID, ET LEURS MÉTHODES D'UTILISATION
  申请人：LOGIGAL THERAPEUTICS INC

  公开号：WO2009012425A2

  公开（公告）日：2009-01-22

  Pharmaceutical compositions containing non-steroidal anti-inflammatory drugs (NSAIDs) and modified NSAIDs and leukotriene antagonists and methods for using such pharmaceutical compositions are provided herein. In a preffered embodiment naproxene 2- (methanesulfonyl) -ethyl ester is used in combination with Zileuton.