4-tert-butyl-N-methyl-N-(naphthalen-1-ylmethyl)benzenesulfonamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-tert-butyl-N-methyl-N-(naphthalen-1-ylmethyl)benzenesulfonamide
• 化学式: C₂₂H₂₅NO₂S
• 分子量: 367.5
• InChiKey: URSTWZXZKZDSEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] RAPID PURIFICATION BY POLYAROMATIC QUENCH REAGENTS<br/>[FR] PURIFICATION RAPIDE PAR REACTIFS DE REFROIDISSEMENT BRUSQUE POLYAROMATIQUES
  申请人：WARNER LAMBERT CO

  公开号：WO2000039055A1

  公开（公告）日：2000-07-06

  Novel polyaromatic hydrocarbon quenching reagents of Formula (I), wherein: P is a polyaromatic hydrocarbon of low chemical reactivity which is soluble; Q is one or more quenching reagents, or an acid or base addition salts thereof, that are capable of selective covalent reaction with unwanted byproducts, or excess reagents; and L is one or more chemically robust linkers or dendritic linkers that join P and Q; are described, as well as methods for their preparation and methods for their use in the rapid purification of synthetic intermediates and products in organic synthesis, combinatorial chemistry and automated organic synthesis.